Esophageal achalasia
Clinical trials for Esophageal achalasia explained in plain language.
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Shorter surgery may be just as effective for treating achalasia
Disease control Not yet recruitingThis trial tests whether a shorter muscle cut during a procedure called POEM works as well as a longer one for people with type II achalasia, a condition where the esophagus fails to push food into the stomach. Fifty participants will be randomly assigned to receive either a shor…
Matched conditions: ESOPHAGEAL ACHALASIA
Sponsor: Assiut University • Aim: Disease control
Last updated Jul 09, 2026 00:00 UTC
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Through-the-Mouth surgery vs keyhole surgery: which works better for a rare swallowing disorder?
Symptom relief Not yet recruitingAchalasia makes it hard to swallow because the valve between the esophagus and stomach stays tight. Researchers randomly assign 220 adults with newly diagnosed achalasia to two procedures that cut that valve muscle: POEM, done through the mouth with no skin cuts, or laparoscopic …
Matched conditions: ESOPHAGEAL ACHALASIA
Sponsor: Minia University • Aim: Symptom relief
Last updated Sep 12, 2026 00:00 UTC
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Cutting across or along? trial tests best way to start POEM for swallowing disorder
Symptom relief Not yet recruitingThis trial tests whether making a horizontal (transverse) or vertical (longitudinal) cut in the esophagus lining during POEM surgery is faster and safer for people with achalasia, a swallowing disorder. About 140 adults in Colombia will be randomly assigned to one of the two inci…
Matched conditions: ESOPHAGEAL ACHALASIA
Phase 3 • Sponsor: Universidad Nacional de Colombia • Aim: Symptom relief
Last updated Jun 27, 2026 09:07 UTC