Esophageal achalasia
Clinical trials for Esophageal achalasia explained in plain language.
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Botox injection could replace surgery for Post-Esophagectomy stomach issues
Disease control Recruiting nowThis study tests whether a Botox injection into the stomach valve works as well as a surgical cut to prevent food from emptying too slowly after esophagus removal. About 170 adults having elective esophagectomy will be randomly assigned to one of the two procedures. Researchers w…
Matched conditions: ESOPHAGEAL ACHALASIA
Phase 2/3 • Sponsor: The Cleveland Clinic • Aim: Disease control
Last updated Jun 27, 2026 09:08 UTC
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Should acid reflux meds be routine after POEM? new trial aims to find out
Disease control Recruiting nowThis study compares two strategies for preventing acid reflux after POEM surgery for achalasia: taking a PPI (Lansoprazole) every day for a year versus taking it only when reflux symptoms occur. About 132 participants will be randomly assigned to one of the two groups. The goal i…
Matched conditions: ESOPHAGEAL ACHALASIA
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated Jun 27, 2026 09:03 UTC
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Could a simple blood test predict esophageal cancer?
Knowledge-focused Recruiting nowThis study is collecting medical history, blood, and tissue samples from 7,000 people with esophageal disorders like GERD or Barrett's esophagus. Researchers hope to find genetic or protein markers that signal a higher risk of developing esophageal cancer. The goal is to enable e…
Matched conditions: ESOPHAGEAL ACHALASIA
Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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Malnutrition may raise risks during throat surgery, study warns
Knowledge-focused Recruiting nowThis study looks at whether malnutrition increases the risk of breathing and kidney problems in people with achalasia undergoing POEM surgery. Researchers will track 60 adults for signs like high carbon dioxide levels and kidney stress. The goal is to better understand which pati…
Matched conditions: ESOPHAGEAL ACHALASIA
Sponsor: Umraniye Education and Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC