ESCC
Clinical trials for ESCC explained in plain language.
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Promising drug cocktail aims to shrink esophageal tumors before surgery
Disease control Not yet recruitingThis study is testing whether giving a combination of three drugs (adebrelimab, nimotuzumab, and chemotherapy) before surgery can help people with a certain type of esophageal cancer. The goal is to shrink or eliminate the tumor before the operation, potentially improving long-te…
Matched conditions: ESCC
Phase: NA • Sponsor: Tianjin Medical University Cancer Institute and Hospital • Aim: Disease control
Last updated May 26, 2026 10:34 UTC
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New triple therapy hopes to outsmart tough esophageal cancer
Disease control Not yet recruitingThis study tests a new three-drug combination for people with advanced esophageal squamous cell carcinoma (ESCC). The drugs include a targeted therapy (becotatug vedotin), an immunotherapy (tislelizumab), and standard chemotherapy. The goal is to see if this combo shrinks tumors …
Matched conditions: ESCC
Phase: PHASE2 • Sponsor: Tianjin Medical University Cancer Institute and Hospital • Aim: Disease control
Last updated May 26, 2026 10:31 UTC
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New drug duo aims to shrink esophageal tumors before surgery
Disease control Not yet recruitingThis study tests whether a combination of two experimental drugs (iparomlimab and tuvonralimab) plus chemotherapy can shrink tumors before surgery in people with a certain type of esophageal cancer. About 26 adults with locally advanced but removable cancer will receive the treat…
Matched conditions: ESCC
Phase: PHASE2 • Sponsor: Tianjin Medical University Cancer Institute and Hospital • Aim: Disease control
Last updated May 26, 2026 10:29 UTC
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New combo therapy aims to extend life for elderly esophageal cancer patients
Disease control Not yet recruitingThis study tests a chemotherapy drug (TAS-102) combined with radiation in people aged 65–85 with advanced esophageal cancer. The goal is to find the best dose and see if the combination helps patients live longer. About 45 participants will receive the treatment, followed by a re…
Matched conditions: ESCC
Phase: PHASE1, PHASE2 • Sponsor: Qianfoshan Hospital • Aim: Disease control
Last updated May 19, 2026 11:47 UTC
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New drug combo may let some esophageal cancer patients skip surgery
Disease control Not yet recruitingThis study tests a drug called adebrelimab combined with chemotherapy before either watchful waiting or surgery for people with a type of esophageal cancer. About 200 participants will receive the treatment first. If their cancer disappears completely, they will be randomly assig…
Matched conditions: ESCC
Phase: PHASE2 • Sponsor: Tianjin Medical University Cancer Institute and Hospital • Aim: Disease control
Last updated May 18, 2026 12:13 UTC
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New combo therapy targets tough esophageal cancer cases
Disease control Not yet recruitingThis study tests a combination of two drugs (SHR-1701 and liposomal irinotecan) in 33 adults with esophageal squamous cell carcinoma who have already received immunotherapy. The goal is to see if the combination can shrink tumors or slow disease progression. Participants will rec…
Matched conditions: ESCC
Phase: PHASE2 • Sponsor: Zhigang Li • Aim: Disease control
Last updated May 13, 2026 15:58 UTC