ENDOMETRIAL SEROUS ADENOCARCINOMA

This study is testing several drug combinations to see if they work better than single drugs at controlling advanced endometrial cancer that has returned or spread. It involves 288 women whose cancer has come back after prior treatment. Researchers are comparing different pairs o…

This study aims to find the most effective drug combination for treating advanced or returning endometrial (uterine) cancer. It randomly assigned 349 patients to receive one of three different chemotherapy and targeted drug regimens. Researchers are comparing how well each combin…

This early-stage study is testing the safety and best dose of a new oral drug (MLN0128) when combined with an existing cancer drug (bevacizumab). It is for adults with recurrent glioblastoma (a type of brain tumor) or other advanced solid tumors that have not responded to standar…

This large, late-stage study is testing whether adding an immunotherapy drug called pembrolizumab to standard chemotherapy works better for treating advanced or recurrent endometrial cancer. It involves over 800 patients with stage III, IV, or returning cancer. The goal is to see…

This study is testing if two methods—a combined PET/CT scan and a special dye used during surgery—can better find cancer that has spread to lymph nodes in patients with high-risk endometrial cancer. The goal is to see if these methods are as good as or better than the standard su…

This early study aims to understand how a drug called triapine affects a specific type of aggressive uterine cancer. Researchers will give a single dose of the drug to 12 patients just before their scheduled cancer-removal surgery. They will then compare tumor tissue samples take…