Immunotherapy plus chemo shows promise for Tough-to-Treat endometrial cancer

NCT ID NCT03914612

Disease control Sponsor: National Cancer Institute (NCI) Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 31, 2026 · Updated 3 times

Summary

This phase III trial tests whether adding the immunotherapy drug pembrolizumab to standard chemotherapy (paclitaxel and carboplatin) helps people with advanced (stage III or IV) or recurrent endometrial cancer. About 800 participants received either the combo or chemo alone. The study aims to see if the combo delays cancer growth and improves response, while also tracking side effects.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance: pembrolizumab (immunotherapy) plus paclitaxel and carboplatin (chemotherapy)
What this could lead to: If it works, this could become a new standard treatment for advanced or recurrent endometrial cancer, helping patients live longer without their cancer growing.
What could go wrong: This is a large phase III trial, but results are not yet final. Adding immunotherapy may increase side effects, and not all patients may benefit. The benefit may be limited to certain tumor types.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

813 people

The number who actually took part.

Started

Aug 2019

Expected to finish

Sep 2026

An estimate. End dates often move.

Lead sponsor

A government research agency

The lead sponsor is the US National Institutes of Health.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Measurable stage III, measurable stage IVA, stage IVB (with or without measurable disease) or recurrent (with or without measurable disease) endometrial cancer. * Pathology report showing results of institutional MMR IHC testing. * Histologic confirmation of the original primary tumor is required (submission of pathology report(s) is required). Patients with the following histologic types are eligible: Endometrioid adenocarcinoma, serous adenocarcinoma, dedifferentiated/undifferentiated carcinoma, clear cell adenocarcinoma, mixed epithelial carcinoma, adenocarcinoma not otherwise specified (N.O.S.). * Submission of tumor specimens for centralized MMR IHC testing is required after Step 1 and before Step 2 registration. * In patients with measurable disease, lesions will be defined and monitored by RECIST version (v) 1.1. Measurable disease is defined as at least one lesion that can be accurately measured in at least one dimension (longest diameter to be recorded). Each lesion must be \>= 10 mm when measured by CT or magnetic resonance imaging (MRI). Lymph nodes must be \>= 15 mm in short axis when measured by CT or MRI. * Patients may have received * NO prior chemotherapy for treatment of endometrial cancer OR * Prior adjuvant chemotherapy (e.g., paclitaxel/carboplatin alone or as a component of concurrent chemotherapy and radiation therapy \[with or without cisplatin\]) provided adjuvant chemotherapy was completed \>= 12 months prior to STEP 2 registration. * Patients may have received prior radiation therapy for treatment of endometrial cancer. Prior radiation therapy may have included pelvic radiation therapy, extended field pelvic/para aortic radiation therapy, intravaginal brachytherapy, and/or palliative radiation therapy. All radiation therapy must be completed at least 4 weeks prior to STEP 2 registration. * Patients may have received prior hormonal therapy for treatment of endometrial cancer. All hormonal therapy must be discontinued at least three weeks prior to STEP 2 registration. * Interval or cytoreductive surgery, after start of treatment on this trial, and prior to documentation of disease progression, is NOT permitted. * Age \>= 18. * Performance status of 0, 1 or 2. * Platelets \>= 100,000/mcl. * Absolute neutrophil count (ANC) \>= 1,500/mcl. * Creatinine =\< 1.5 x institutional/laboratory upper limit of normal (ULN). * Total serum bilirubin level =\< 1.5 x ULN (patients with known Gilbert's disease who have bilirubin level =\< 3 x ULN may be enrolled). * Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) =\< 3 x ULN. * Thyroid stimulating hormone (TSH) within normal limits. If TSH is not within normal range despite no symptoms of thyroid dysfunction, normal Free T4 level is required. * Human immunodeficiency virus (HIV)-infected patients on effective anti-retroviral therapy with undetectable viral load within 6 months of Step 2 registration are eligible for this trial. * For patients of child bearing potential: negative urine or serum pregnancy test. If the urine test is positive or cannot be confirmed as negative, a serum pregnancy test is required. * Administration of study drugs (pembrolizumab \[MK-3475\], paclitaxel, carboplatin) may have an adverse effect on pregnancy and poses a risk to the human fetus, including embryo-lethality. Women of childbearing potential (WOCBP) must agree to use adequate contraception (hormonal or barrier method of birth control; abstinence) from at least 14 days prior to Step 2 registration (for oral contraceptives), during treatment, and for 120 days after the last dose of study medication. Should a woman become pregnant or suspect she is pregnant while she is participating in this study, she should inform her treating physician immediately. Patients will be considered of nonreproductive potential if they are either: * Postmenopausal (defined as at least 12 months with no menses without an alternative medical cause; in women \< 45 years of age, a high follicle stimulating hormone (FSH) level in the postmenopausal range may be used to confirm a postmenopausal state in women not using hormonal contraception or hormonal replacement therapy. In the absence of 12 months of amenorrhea, a single FSH measurement is insufficient); OR * Have a hysterectomy and/or bilateral oophorectomy, bilateral salpingectomy or bilateral tubal ligation/occlusion, at least 6 weeks prior to Step 2 registration; OR * Have a congenital or acquired condition that prevents childbearing. * Patients with a prior or concurrent malignancy whose natural history or treatment does not have the potential to interfere with the safety or efficacy assessment of the investigational regimen are eligible for this trial. * The patient or a legally authorized representative must provide study-specific informed consent prior to study entry and, for patients treated in the United States (U.S.), authorization permitting release of personal health information. Exclusion Criteria: * Patients with prior treatment with anti-PD-1, anti-PD-L1 or anti-CTLA-4 therapeutic antibody or other similar agents. * Patients who have a history of a severe hypersensitivity reaction to monoclonal antibody or pembrolizumab (MK-3475) and/or its excipients; and/or a severe hypersensitivity reaction to paclitaxel and/or carboplatin. * Patients who are currently participating and receiving cancer-directed study therapy or have participated in a study of an investigational agent and received cancer-directed study therapy within 4 weeks prior to Step 2 registration. * Patients who have a diagnosis of immunodeficiency or are receiving systemic steroid therapy or any other form of immunosuppressive therapy within 7 days prior to Step 2 registration. * Patients who have received steroids as CT scan contrast premedication may be enrolled. * The use of inhaled or topical corticosteroids is allowed. * The use of mineralocorticoids (e.g., fludrocortisone) for patients with orthostatic hypotension or adrenocortical insufficiency is allowed. * The use of physiologic doses of corticosteroids may be approved after consultation with the study chair. * Patients with treated brain metastases are eligible if follow-up brain imaging after central nervous system (CNS)-directed therapy shows no evidence of progression, and they have been off steroids for at least 4 weeks prior to Step 2 registration and remain clinically stable. * Patients with active autoimmune disease or history of autoimmune disease that might recur, which may affect vital organ function or require immune suppressive treatment including systemic corticosteroids. This includes, but is not limited to, patients with a history of immune related neurologic disease, multiple sclerosis, autoimmune (demyelinating) neuropathy, Guillain-Barre syndrome, myasthenia gravis; systemic autoimmune disease such as systemic lupus erythematosus (SLE), connective tissue diseases, scleroderma, inflammatory bowel disease (IBD), Crohn's, ulcerative colitis, hepatitis; and patients with a history of toxic epidermal necrolysis (TEN), Stevens-Johnson syndrome, or phospholipid syndrome because of the risk of recurrence or exacerbation of disease. * Patients with vitiligo, endocrine deficiencies including type I diabetes mellitus, thyroiditis managed with replacement hormones including physiologic corticosteroids are eligible. * Patients with rheumatoid arthritis and other arthropathies, Sjogren's syndrome and psoriasis controlled with topical medication and patients with positive serology, such as antinuclear antibodies (ANA), anti-thyroid antibodies should be evaluated for the presence of target organ involvement and potential need for systemic treatment but should otherwise be eligible. * Patients who have a history of (non-infectious) pneumonitis that required steroids, or current pneumonitis. * Uncontrolled intercurrent illness including, but not limited to: ongoing or active infection (except for uncomplicated urinary tract infection), interstitial lung disease or active, non-infectious pneumonitis, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements. * Known clinically significant liver disease, including active viral, alcoholic, or other hepatitis; and cirrhosis. * For patients with evidence of chronic hepatitis B virus (HBV) infection, the HBV viral load must be undetectable on suppressive therapy, if indicated. * Patients with a history of hepatitis C virus (HCV) infection must have been treated and cured. For patients with HCV infection who are currently on treatment, they are eligible if they have an undetectable HCV viral load. * Pregnant or lactating patients.

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Conditions

The condition(s) this trial relates to.

carcinosarcoma endometrial cancer endometrial carcinoma endometrial clear cell adenocarcinoma endometrial endometrioid adenocarcinoma endometrial mixed adenocarcinoma endometrial serous adenocarcinoma endometrial undifferentiated carcinoma endometrium adenocarcinoma endometrium neoplasm uterine corpus cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

Adams Cancer Center

Gettysburg, Pennsylvania, 17325, United States
Alaska Women's Cancer Care

Anchorage, Alaska, 99508, United States
Algoma District Cancer Program Sault Area Hospital

Sault Ste. Marie, Ontario, P6B 0A8, Canada
Allan Blair Cancer Centre

Regina, Saskatchewan, S4T 7T1, Canada
Alta Bates Summit Medical Center-Herrick Campus

Berkeley, California, 94704, United States
Asan Medical Center

Seoul, 05505, South Korea
Ascension Saint Vincent Indianapolis Hospital

Indianapolis, Indiana, 46260, United States
Asplundh Cancer Pavilion

Willow Grove, Pennsylvania, 19090, United States
Atrium Health Cabarrus/LCI-Concord

Concord, North Carolina, 28025, United States
Aultman Health Foundation

Canton, Ohio, 44710, United States
Aurora Bay Area Medical Group-Marinette

Marinette, Wisconsin, 54143, United States
Aurora BayCare Medical Center

Green Bay, Wisconsin, 54311, United States
Aurora Cancer Care-Grafton

Grafton, Wisconsin, 53024, United States
Aurora Cancer Care-Kenosha South

Kenosha, Wisconsin, 53142, United States
Aurora Cancer Care-Milwaukee

Milwaukee, Wisconsin, 53209, United States
Aurora Cancer Care-Milwaukee West

Wauwatosa, Wisconsin, 53226, United States
Aurora Cancer Care-Racine

Racine, Wisconsin, 53406, United States
Aurora Cancer Care-Southern Lakes VLCC

Burlington, Wisconsin, 53105, United States
Aurora Health Care Germantown Health Center

Germantown, Wisconsin, 53022, United States
Aurora Medical Center in Summit

Summit, Wisconsin, 53066, United States
Aurora Saint Luke's Medical Center

Milwaukee, Wisconsin, 53215, United States
Aurora Sinai Medical Center

Milwaukee, Wisconsin, 53233, United States
Aurora West Allis Medical Center

West Allis, Wisconsin, 53227, United States
Avera Cancer Institute

Sioux Falls, South Dakota, 57105, United States
Banner North Colorado Medical Center

Greeley, Colorado, 80631, United States
Banner North Colorado Medical Center - Loveland Campus

Loveland, Colorado, 80539, United States
Baptist Memorial Hospital and Cancer Center-Memphis

Memphis, Tennessee, 38120, United States
Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center

Houston, Texas, 77030, United States
Baystate Medical Center

Springfield, Massachusetts, 01199, United States
Ben Taub General Hospital

Houston, Texas, 77030, United States
Beth Israel Deaconess Medical Center/Winchester Center for Cancer Care

Winchester, Massachusetts, 01890, United States
Billings Clinic Cancer Center

Billings, Montana, 59101, United States
Bronson Methodist Hospital

Kalamazoo, Michigan, 49007, United States
CHUM - Centre Hospitalier de l'Universite de Montreal

Montreal, Quebec, H2X 3E4, Canada
CTCA at Southeastern Regional Medical Center

Newnan, Georgia, 30265, United States
CTCA at Western Regional Medical Center

Goodyear, Arizona, 85338, United States
California Pacific Medical Center-Pacific Campus

San Francisco, California, 94115, United States
Cancer Care Center of O'Fallon

O'Fallon, Illinois, 62269, United States
Cancer Care Specialists of Illinois - Decatur

Decatur, Illinois, 62526, United States
Cancer Care and Hematology-Fort Collins

Fort Collins, Colorado, 80528, United States
Cancer Hematology Centers - Flint

Flint, Michigan, 48503, United States
Carle Cancer Center

Urbana, Illinois, 61801, United States
Carle Physician Group-Mattoon/Charleston

Mattoon, Illinois, 61938, United States
Carle at The Riverfront

Danville, Illinois, 61832, United States
Carolinas Medical Center/Levine Cancer Institute

Charlotte, North Carolina, 28203, United States
Case Western Reserve University

Cleveland, Ohio, 44106, United States
Cedars-Sinai Medical Center

Los Angeles, California, 90048, United States
Centro Comprensivo de Cancer de UPR

San Juan, 00927, Puerto Rico
City of Hope Antelope Valley

Lancaster, California, 93534, United States
City of Hope Comprehensive Cancer Center

Duarte, California, 91010, United States
City of Hope South Pasadena

South Pasadena, California, 91030, United States
City of Hope Upland

Upland, California, 91786, United States
Cleveland Clinic Cancer Center/Fairview Hospital

Cleveland, Ohio, 44111, United States
Cleveland Clinic Foundation

Cleveland, Ohio, 44195, United States
Community Cancer Center East

Indianapolis, Indiana, 46219, United States
Community Cancer Center North

Indianapolis, Indiana, 46256, United States
Community Cancer Center South

Indianapolis, Indiana, 46227, United States
Community Cancer Institute

Clovis, California, 93611, United States
Community Hospital of Anaconda

Anaconda, Montana, 59711, United States
Community Medical Center

Toms River, New Jersey, 08755, United States
Community Medical Center

Scranton, Pennsylvania, 18510, United States
Cooper Hospital University Medical Center

Camden, New Jersey, 08103, United States
Cooperman Barnabas Medical Center

Livingston, New Jersey, 07039, United States
Corewell Health Grand Rapids Hospitals - Butterworth Hospital

Grand Rapids, Michigan, 49503, United States
Crossroads Cancer Center

Effingham, Illinois, 62401, United States
Danbury Hospital

Danbury, Connecticut, 06810, United States
Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center

Lebanon, New Hampshire, 03756, United States
East Jefferson General Hospital

Metairie, Louisiana, 70006, United States
Ehime University Hospital

Tōon, Ehime, 791-0295, Japan
Eisenhower Medical Center

Rancho Mirage, California, 92270, United States
Emory Saint Joseph's Hospital

Atlanta, Georgia, 30342, United States
Emory University Hospital Midtown

Atlanta, Georgia, 30308, United States
Emory University Hospital/Winship Cancer Institute

Atlanta, Georgia, 30322, United States
Ephrata Cancer Center

Ephrata, Pennsylvania, 17522, United States
Essentia Health Cancer Center

Duluth, Minnesota, 55805, United States
Florida Cancer Specialists - Bradenton Cancer Center

Bradenton, Florida, 34205, United States
Florida Cancer Specialists - Sarasota

Sarasota, Florida, 34232, United States
Florida Cancer Specialists - Sarasota Downtown

Sarasota, Florida, 34239, United States
Florida Cancer Specialists - Venice Island

Venice, Florida, 34285, United States
Florida Cancer Specialists - Venice Pinebrook

Venice, Florida, 34275, United States
Forbes Hospital

Monroeville, Pennsylvania, 15146, United States
Franciscan Health Indianapolis

Indianapolis, Indiana, 46237, United States
Franciscan Health Mooresville

Mooresville, Indiana, 46158, United States
Gangnam Severance Hospital

Seoul, 06273, South Korea
Geauga Hospital

Chardon, Ohio, 44024, United States
Geisinger Cancer Services-Pottsville

Pottsville, Pennsylvania, 17901, United States
Geisinger Medical Center

Danville, Pennsylvania, 17822, United States
Geisinger Medical Center-Cancer Center Hazleton

Hazleton, Pennsylvania, 18201, United States
Geisinger Wyoming Valley/Henry Cancer Center

Wilkes-Barre, Pennsylvania, 18711, United States
Genesee Hematology Oncology PC

Flint, Michigan, 48503, United States
Genesys Hurley Cancer Institute

Flint, Michigan, 48503, United States
Good Samaritan Hospital - Cincinnati

Cincinnati, Ohio, 45220, United States
Grady Health System

Atlanta, Georgia, 30303, United States
Greater Baltimore Medical Center

Baltimore, Maryland, 21204, United States
Harold Alfond Center for Cancer Care

Augusta, Maine, 04330, United States
Hartford Hospital

Hartford, Connecticut, 06102, United States
Health Sciences North

Greater Sudbury, Ontario, P3E 5J1, Canada
Helen F Graham Cancer Center

Newark, Delaware, 19713, United States
Highland Hospital

Rochester, New York, 14620, United States
Hillcrest Hospital Cancer Center

Mayfield Heights, Ohio, 44124, United States
Hopital de la Cite-de-la-Sante

Laval, Quebec, H7M 3L9, Canada
Houston Methodist Hospital

Houston, Texas, 77030, United States
Houston Methodist Sugar Land Hospital

Sugar Land, Texas, 77479, United States
Houston Methodist The Woodlands Hospital

The Woodlands, Texas, 77385, United States
Huntsman Cancer Institute/University of Utah

Salt Lake City, Utah, 84112, United States
Indiana University/Melvin and Bren Simon Cancer Center

Indianapolis, Indiana, 46202, United States
Ingalls Memorial Hospital

Harvey, Illinois, 60426, United States
Island Gynecologic Oncology

Brightwaters, New York, 11718, United States
Jefferson Hospital

Jefferson Hills, Pennsylvania, 15025, United States
Jersey Shore Medical Center

Neptune City, New Jersey, 07753, United States
John Muir Medical Center-Walnut Creek

Walnut Creek, California, 94598, United States
Johns Hopkins University/Sidney Kimmel Cancer Center

Baltimore, Maryland, 21287, United States
Juravinski Cancer Centre at Hamilton Health Sciences

Hamilton, Ontario, L8V 5C2, Canada
Kadlec Clinic Hematology and Oncology

Kennewick, Washington, 99336, United States
Kaiser Permanente Downtown Commons

Sacramento, California, 95814, United States
Kaiser Permanente Los Angeles Medical Center

Los Angeles, California, 90027, United States
Kaiser Permanente Medical Center - Santa Clara

Santa Clara, California, 95051, United States
Kaiser Permanente San Leandro

San Leandro, California, 94577, United States
Kaiser Permanente South Bay

Harbor City, California, 90710, United States
Kaiser Permanente-Baldwin Park

Baldwin Park, California, 91706, United States
Kaiser Permanente-Bellflower

Bellflower, California, 90706, United States
Kaiser Permanente-Irvine

Irvine, California, 92618, United States
Kaiser Permanente-Oakland

Oakland, California, 94611, United States
Kaiser Permanente-Riverside

Riverside, California, 92505, United States
Kaiser Permanente-Roseville

Roseville, California, 95661, United States
Kaiser Permanente-San Diego Zion

San Diego, California, 92120, United States
Kaiser Permanente-San Francisco

San Francisco, California, 94115, United States
Kaiser Permanente-San Marcos

San Marcos, California, 92078, United States
Kaiser Permanente-Santa Teresa-San Jose

San Jose, California, 95119, United States
Kaiser Permanente-South San Francisco

South San Francisco, California, 94080, United States
Kaiser Permanente-Vallejo

Vallejo, California, 94589, United States
Kaiser Permanente-Walnut Creek

Walnut Creek, California, 94596, United States
Kapiolani Medical Center for Women and Children

Honolulu, Hawaii, 96826, United States
Keimyung University-Dongsan Medical Center

Dalseo-gu, Daegu, 42601, South Korea
Kingston Health Sciences Centre

Kingston, Ontario, K7L 2V7, Canada
Korea Cancer Center Hospital

Seoul, 139-706, South Korea
Kure Medical Center and Chugoku Cancer Center

Kure, Hiroshima, 737, Japan
Kyungpook National University Chilgok Hospital

Daegu, 41404, South Korea
LSU Health Baton Rouge-North Clinic

Baton Rouge, Louisiana, 70805, United States
Lafayette Family Cancer Center-EMMC

Brewer, Maine, 04412, United States
Lahey Clinic

Burlington, Massachusetts, 01805, United States
Lakeridge Health Oshawa

Oshawa, Ontario, L1G 2B9, Canada
Lancaster General Ann B Barshinger Cancer Institute

Lancaster, Pennsylvania, 17601, United States
Lancaster General Hospital

Lancaster, Pennsylvania, 17602, United States
Laura and Isaac Perlmutter Cancer Center at NYU Langone

New York, New York, 10016, United States
Legacy Good Samaritan Hospital and Medical Center

Portland, Oregon, 97210, United States
Legacy Meridian Park Hospital

Tualatin, Oregon, 97062, United States
Legacy Salmon Creek Hospital

Vancouver, Washington, 98686, United States
Lehigh Valley Hospital - Muhlenberg

Bethlehem, Pennsylvania, 18017, United States
Lehigh Valley Hospital-Cedar Crest

Allentown, Pennsylvania, 18103, United States
Lewis Cancer and Research Pavilion at Saint Joseph's/Candler

Savannah, Georgia, 31405, United States
London Regional Cancer Program

London, Ontario, N6A 4L6, Canada
Long Island Jewish Medical Center

New Hyde Park, New York, 11040, United States
Los Angeles General Medical Center

Los Angeles, California, 90033, United States
Lowell General Hospital

Lowell, Massachusetts, 01854, United States
Loyola University Medical Center

Maywood, Illinois, 60153, United States
Luminis Health Anne Arundel Medical Center

Annapolis, Maryland, 21401, United States
MD Anderson Cancer Center at Cooper-Voorhees

Voorhees Township, New Jersey, 08043, United States
MaineHealth Cancer Care and IV Therapy - Sanford

Sanford, Maine, 04073, United States
MaineHealth Maine Medical Center - Biddeford

Biddeford, Maine, 04005, United States
MaineHealth Maine Medical Center- Scarborough

Scarborough, Maine, 04074, United States
MaineHealth Waldo Hospital

Belfast, Maine, 04915, United States
Margaret R Pardee Memorial Hospital

Hendersonville, North Carolina, 28791, United States
Marshfield Medical Center - Minocqua

Minocqua, Wisconsin, 54548, United States
Marshfield Medical Center - Weston

Weston, Wisconsin, 54476, United States
Marshfield Medical Center-EC Cancer Center

Eau Claire, Wisconsin, 54701, United States
Marshfield Medical Center-Marshfield

Marshfield, Wisconsin, 54449, United States
Marshfield Medical Center-Rice Lake

Rice Lake, Wisconsin, 54868, United States
Marshfield Medical Center-River Region at Stevens Point

Stevens Point, Wisconsin, 54482, United States
Mayo Clinic in Rochester

Rochester, Minnesota, 55905, United States
MedStar Franklin Square Medical Center/Weinberg Cancer Institute

Baltimore, Maryland, 21237, United States
MedStar Washington Hospital Center

Washington D.C., District of Columbia, 20010, United States
Medical Center of the Rockies

Loveland, Colorado, 80538, United States
Medical University of South Carolina

Charleston, South Carolina, 29425, United States
Memorial Health University Medical Center

Savannah, Georgia, 31404, United States
Memorial Hospital North

Colorado Springs, Colorado, 80920, United States
Memorial Sloan Kettering Basking Ridge

Basking Ridge, New Jersey, 07920, United States
Memorial Sloan Kettering Bergen

Montvale, New Jersey, 07645, United States
Memorial Sloan Kettering Cancer Center

New York, New York, 10065, United States
Memorial Sloan Kettering Commack

Commack, New York, 11725, United States
Memorial Sloan Kettering Monmouth

Middletown, New Jersey, 07748, United States
Memorial Sloan Kettering Nassau

Uniondale, New York, 11553, United States
Memorial Sloan Kettering Westchester

Harrison, New York, 10604, United States
Mercy Cancer Center - Sacramento

Sacramento, California, 95816, United States
Mercy Hospital Saint Louis

St Louis, Missouri, 63141, United States
Mercy Hospital Springfield

Springfield, Missouri, 65804, United States
Mercy Oncology Center

Redding, California, 96002, United States
Mercy Regional Cancer Center

Redding, California, 96001, United States
Methodist Willowbrook Hospital

Houston, Texas, 77070, United States
MetroHealth Medical Center

Cleveland, Ohio, 44109, United States
Miami Valley Hospital South

Centerville, Ohio, 45459, United States
Midwestern Regional Medical Center

Zion, Illinois, 60099, United States
Mississippi Baptist Medical Center

Jackson, Mississippi, 39202, United States
Monmouth Medical Center

Long Branch, New Jersey, 07740, United States
Monmouth Medical Center Southern Campus

Lakewood, New Jersey, 08701, United States
Monongalia Hospital

Morgantown, West Virginia, 26505, United States
Montefiore Medical Center - Moses Campus

The Bronx, New York, 10467, United States
Montefiore Medical Center-Einstein Campus

The Bronx, New York, 10461, United States
Mount Sinai Chelsea

New York, New York, 10011, United States
Mount Sinai Hospital

New York, New York, 10029, United States
MultiCare Gig Harbor Medical Park

Gig Harbor, Washington, 98335, United States
MultiCare Good Samaritan Hospital

Puyallup, Washington, 98372, United States
MultiCare Tacoma General Hospital

Tacoma, Washington, 98405, United States
Munson Medical Center

Traverse City, Michigan, 49684, United States
NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro

Jonesboro, Arkansas, 72401, United States
NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center

New York, New York, 10032, United States
NYP/Weill Cornell Medical Center

New York, New York, 10065, United States
NYU Langone Hospital - Long Island

Mineola, New York, 11501, United States
Naval Medical Center -San Diego

San Diego, California, 92134, United States
Nebraska Cancer Specialists/Oncology Hematology West PC

Grand Island, Nebraska, 68803, United States
Nebraska Methodist Hospital

Omaha, Nebraska, 68114, United States
Neurosurgeons of New Jersey-Ridgewood

Ridgewood, New Jersey, 07450, United States
New York-Presbyterian/Brooklyn Methodist Hospital

Brooklyn, New York, 11215, United States
Niigata University Medical and Dental Hospital

Niigata, Niigata, 951-8520, Japan
NorthShore University HealthSystem-Evanston Hospital

Evanston, Illinois, 60201, United States
NorthShore University HealthSystem-Glenbrook Hospital

Glenview, Illinois, 60026, United States
NorthShore University HealthSystem-Highland Park Hospital

Highland Park, Illinois, 60035, United States
Northeast Georgia Medical Center-Gainesville

Gainesville, Georgia, 30501, United States
Northside Hospital

Atlanta, Georgia, 30342, United States
Northwell Health Imbert Cancer Center

Bay Shore, New York, 11706, United States
Northwell Health/Center for Advanced Medicine

Lake Success, New York, 11042, United States
Northwest Cancer Center - Crown Point

Crown Point, Indiana, 46307, United States
Northwest Cancer Center - Hobart

Hobart, Indiana, 46342, United States
Northwest Cancer Center - Valparaiso

Valparaiso, Indiana, 46383, United States
Northwest Oncology LLC

Dyer, Indiana, 46311, United States
Northwestern Medicine Cancer Center Delnor

Geneva, Illinois, 60134, United States
Northwestern Medicine Cancer Center Warrenville

Warrenville, Illinois, 60555, United States
Northwestern University

Chicago, Illinois, 60611, United States
Norwalk Hospital

Norwalk, Connecticut, 06856, United States
Novant Health New Hanover Regional Medical Center

Wilmington, North Carolina, 28401, United States
Ochsner Baptist Medical Center

New Orleans, Louisiana, 70115, United States
Ochsner Medical Center Jefferson

New Orleans, Louisiana, 70121, United States
Odette Cancer Centre- Sunnybrook Health Sciences Centre

Toronto, Ontario, M4N 3M5, Canada
Ohio State University Comprehensive Cancer Center

Columbus, Ohio, 43210, United States
Oklahoma Cancer Specialists and Research Institute-Tulsa

Tulsa, Oklahoma, 74146, United States
Our Lady of The Lake

Baton Rouge, Louisiana, 70808, United States
Our Lady of the Lake Medical Oncology

Baton Rouge, Louisiana, 70817, United States
Our Lady of the Lake Physician Group

Baton Rouge, Louisiana, 70808, United States
Palo Alto Medical Foundation-Gynecologic Oncology

Mountain View, California, 94040, United States
Palo Alto Medical Foundation-Sunnyvale

Sunnyvale, California, 94086, United States
Parkland Memorial Hospital

Dallas, Texas, 75235, United States
Penobscot Bay Medical Center

Rockport, Maine, 04856, United States
Penrose-Saint Francis Healthcare

Colorado Springs, Colorado, 80907, United States
Piedmont Fayette Hospital

Fayetteville, Georgia, 30214, United States
Poudre Valley Hospital

Fort Collins, Colorado, 80524, United States
Prisma Health Cancer Institute - Faris

Greenville, South Carolina, 29605, United States
Prisma Health Cancer Institute - Seneca

Seneca, South Carolina, 29672, United States
ProHealth Oconomowoc Memorial Hospital

Oconomowoc, Wisconsin, 53066, United States
ProMedica Flower Hospital

Sylvania, Ohio, 43560, United States
Providence Portland Medical Center

Portland, Oregon, 97213, United States
Providence Saint Vincent Medical Center

Portland, Oregon, 97225, United States
Queen's Medical Center

Honolulu, Hawaii, 96813, United States
Rapid City Regional Hospital

Rapid City, South Dakota, 57701, United States
Reading Hospital

West Reading, Pennsylvania, 19611, United States
Riverside Methodist Hospital

Columbus, Ohio, 43214, United States
Robert Wood Johnson University Hospital Somerset

Somerville, New Jersey, 08876, United States
Roswell Park Cancer Institute

Buffalo, New York, 14263, United States
Royal Victoria Regional Health Centre

Barrie, Ontario, L4M 6M2, Canada
Rush MD Anderson Cancer Center

Chicago, Illinois, 60612, United States
Rutgers Cancer Institute of New Jersey

New Brunswick, New Jersey, 08903, United States
Saint Agnes Hospital

Baltimore, Maryland, 21229, United States
Saint Alphonsus Cancer Care Center-Boise

Boise, Idaho, 83706, United States
Saint Alphonsus Cancer Care Center-Caldwell

Caldwell, Idaho, 83605, United States
Saint Alphonsus Cancer Care Center-Nampa

Nampa, Idaho, 83687, United States
Saint Alphonsus Cancer Care Center-Ontario

Ontario, Oregon, 97914, United States
Saint Catherine Hospital

Indianapolis, Indiana, 46312, United States
Saint Charles Health System

Bend, Oregon, 97701, United States
Saint Elizabeth Healthcare Edgewood

Edgewood, Kentucky, 41017, United States
Saint Francis Cancer Center

Greenville, South Carolina, 29607, United States
Saint Francis Hospital

Greenville, South Carolina, 29601, United States
Saint Joseph Hospital - Orange

Orange, California, 92868, United States
Saint Luke's Cancer Institute - Boise

Boise, Idaho, 83712, United States
Saint Luke's Cancer Institute - Fruitland

Fruitland, Idaho, 83619, United States
Saint Luke's Cancer Institute - Meridian

Meridian, Idaho, 83642, United States
Saint Luke's Cancer Institute - Nampa

Nampa, Idaho, 83687, United States
Saint Luke's Cancer Institute - Twin Falls

Twin Falls, Idaho, 83301, United States
Saint Luke's Hospital of Kansas City

Kansas City, Missouri, 64111, United States
Saint Mary Medical Center

Hobart, Indiana, 46342, United States
Saitama Medical University International Medical Center

Saitama, 350-1298, Japan
Samsung Changwon Hospital

Seoul, Gyeongsangnam-do, 51353, South Korea
Sanford Bismarck Medical Center

Bismarck, North Dakota, 58501, United States
Sanford Broadway Medical Center

Fargo, North Dakota, 58122, United States
Sanford Cancer Center Oncology Clinic

Sioux Falls, South Dakota, 57104, United States
Sanford Joe Lueken Cancer Center

Bemidji, Minnesota, 56601, United States
Sanford Roger Maris Cancer Center

Fargo, North Dakota, 58122, United States
Sarasota Memorial Hospital

Sarasota, Florida, 34239, United States
Saskatoon Cancer Centre

Saskatoon, Saskatchewan, S7N 4H4, Canada
Sechler Family Cancer Center

Lebanon, Pennsylvania, 17042, United States
Seoul National University Bundang Hospital

Seongnam, Kyeonggi-do, 463-707, South Korea
Sibley Memorial Hospital

Washington D.C., District of Columbia, 20016, United States
Sinai Hospital of Baltimore

Baltimore, Maryland, 21215, United States
Smilow Cancer Hospital Care Center - Guilford

Guilford, Connecticut, 06437, United States
Smilow Cancer Hospital Care Center - Waterford

Waterford, Connecticut, 06385, United States
Smilow Cancer Hospital Care Center at Saint Francis

Hartford, Connecticut, 06105, United States
Smilow Cancer Hospital Care Center-Trumbull

Trumbull, Connecticut, 06611, United States
Smilow Cancer Hospital-Torrington Care Center

Torrington, Connecticut, 06790, United States
Smilow Cancer Hospital-Waterbury Care Center

Waterbury, Connecticut, 06708, United States
Southeastern Medical Oncology Center-Clinton

Clinton, North Carolina, 28328, United States
Southeastern Medical Oncology Center-Goldsboro

Goldsboro, North Carolina, 27534, United States
Southeastern Medical Oncology Center-Jacksonville

Jacksonville, North Carolina, 28546, United States
Southwest Gynecologic Oncology Associates Inc

Albuquerque, New Mexico, 87106, United States
Springfield Clinic

Springfield, Illinois, 62702, United States
Stamford Hospital/Bennett Cancer Center

Stamford, Connecticut, 06904, United States
State University of New York Upstate Medical University

Syracuse, New York, 13210, United States
Staten Island University Hospital

Staten Island, New York, 10305, United States
Stony Brook University Medical Center

Stony Brook, New York, 11794, United States
Summa Health System - Akron Campus

Akron, Ohio, 44304, United States
Swedish Medical Center-First Hill

Seattle, Washington, 98122, United States
The Community Hospital

Munster, Indiana, 46321, United States
The Hospital of Central Connecticut

New Britain, Connecticut, 06050, United States
The Mark H Zangmeister Center

Columbus, Ohio, 43219, United States
The Moncton Hospital

Moncton, New Brunswick, E1C 6Z8, Canada
The New York Hospital Medical Center of Queens

Flushing, New York, 11355, United States
The Valley Hospital - Luckow Pavilion

Paramus, New Jersey, 07652, United States
Thomas Jefferson University Hospital

Philadelphia, Pennsylvania, 19107, United States
Trinity Health Saint Joseph Mercy Hospital Ann Arbor

Ann Arbor, Michigan, 48106, United States
UC Comprehensive Cancer Center at Silver Cross

New Lenox, Illinois, 60451, United States
UC Irvine Health/Chao Family Comprehensive Cancer Center

Orange, California, 92868, United States
UC San Diego Moores Cancer Center

La Jolla, California, 92093, United States
UCHealth Greeley Hospital

Greeley, Colorado, 80631, United States
UCHealth Memorial Hospital Central

Colorado Springs, Colorado, 80909, United States
UCLA / Jonsson Comprehensive Cancer Center

Los Angeles, California, 90095, United States
UCSF Medical Center-Mission Bay

San Francisco, California, 94158, United States
UH Seidman Cancer Center at Lake Health Mentor Campus

Mentor, Ohio, 44060, United States
UH Seidman Cancer Center at Saint John Medical Center

Westlake, Ohio, 44145, United States
UHHS-Chagrin Highlands Medical Center

Beachwood, Ohio, 44122, United States
UM Upper Chesapeake Medical Center

Bel Air, Maryland, 21014, United States
UMass Memorial Medical Center - Memorial Division

Worcester, Massachusetts, 01605, United States
UNC Lineberger Comprehensive Cancer Center

Chapel Hill, North Carolina, 27599, United States
UPMC Hillman Cancer Center

Pittsburgh, Pennsylvania, 15232, United States
UPMC Hillman Cancer Center - Monroeville

Monroeville, Pennsylvania, 15146, United States
UPMC-Johnstown/John P. Murtha Regional Cancer Center

Johnstown, Pennsylvania, 15901, United States
UPMC-Magee Womens Hospital

Pittsburgh, Pennsylvania, 15213, United States
USC / Norris Comprehensive Cancer Center

Los Angeles, California, 90033, United States
UT Southwestern/Simmons Cancer Center-Dallas

Dallas, Texas, 75390, United States
UW Cancer Center at ProHealth Care

Waukesha, Wisconsin, 53188, United States
University Health Network-Princess Margaret Hospital

Toronto, Ontario, M5G 2M9, Canada
University Medical Center New Orleans

New Orleans, Louisiana, 70112, United States
University of Alabama at Birmingham Cancer Center

Birmingham, Alabama, 35233, United States
University of Arkansas for Medical Sciences

Little Rock, Arkansas, 72205, United States
University of California Davis Comprehensive Cancer Center

Sacramento, California, 95817, United States
University of Chicago Comprehensive Cancer Center

Chicago, Illinois, 60637, United States
University of Chicago Medicine-Orland Park

Orland Park, Illinois, 60462, United States
University of Cincinnati Cancer Center-UC Medical Center

Cincinnati, Ohio, 45219, United States
University of Cincinnati Cancer Center-West Chester

West Chester, Ohio, 45069, United States
University of Illinois

Chicago, Illinois, 60612, United States
University of Iowa/Holden Comprehensive Cancer Center

Iowa City, Iowa, 52242, United States
University of Kansas Cancer Center

Kansas City, Kansas, 66160, United States
University of Kansas Clinical Research Center

Fairway, Kansas, 66205, United States
University of Kansas Hospital-Indian Creek Campus

Overland Park, Kansas, 66211, United States
University of Kansas Hospital-Westwood Cancer Center

Westwood, Kansas, 66205, United States
University of Maryland Shore Medical Center at Easton

Easton, Maryland, 21601, United States
University of Maryland/Greenebaum Cancer Center

Baltimore, Maryland, 21201, United States
University of Michigan Health - Sparrow Lansing

Lansing, Michigan, 48912, United States
University of Michigan Rogel Cancer Center

Ann Arbor, Michigan, 48109, United States
University of Mississippi Medical Center

Jackson, Mississippi, 39216, United States
University of Nebraska Medical Center

Omaha, Nebraska, 68198, United States
University of New Mexico Cancer Center

Albuquerque, New Mexico, 87106, United States
University of Oklahoma Health Sciences Center

Oklahoma City, Oklahoma, 73104, United States
University of Rochester

Rochester, New York, 14642, United States
University of Utah Sugarhouse Health Center

Salt Lake City, Utah, 84106, United States
University of Vermont Medical Center

Burlington, Vermont, 05401, United States
University of Virginia Cancer Center

Charlottesville, Virginia, 22908, United States
University of Wisconsin Carbone Cancer Center - University Hospital

Madison, Wisconsin, 53792, United States
VCU Massey Comprehensive Cancer Center

Richmond, Virginia, 23298, United States
Valley Health System Ridgewood Campus

Ridgewood, New Jersey, 07450, United States
Valley Health System-Hematology/Oncology

Westwood, New Jersey, 07675, United States
Valley Medical Center

Renton, Washington, 98055, United States
Valley Medical Group - Wayne Multispecialty Practice

Wayne, New Jersey, 07470, United States
Vanderbilt University/Ingram Cancer Center

Nashville, Tennessee, 37232, United States
Vince Lombardi Cancer Clinic - Oshkosh

Oshkosh, Wisconsin, 54904, United States
Vince Lombardi Cancer Clinic-Sheboygan

Sheboygan, Wisconsin, 53081, United States
Vince Lombardi Cancer Clinic-Two Rivers

Two Rivers, Wisconsin, 54241, United States
Wake Forest University Health Sciences

Winston-Salem, North Carolina, 27157, United States
Walter Reed National Military Medical Center

Bethesda, Maryland, 20889-5600, United States
Washington University School of Medicine

St Louis, Missouri, 63110, United States
WellSpan Health-York Cancer Center

York, Pennsylvania, 17403, United States
WellSpan Health-York Hospital

York, Pennsylvania, 17403, United States
WellSpan Medical Oncology and Hematology

Hanover, Pennsylvania, 17331, United States
WellStar Cobb Hospital

Austell, Georgia, 30106, United States
WellStar Health System Inc

Marietta, Georgia, 30060, United States
WellStar North Fulton Hospital

Roswell, Georgia, 30076, United States
WellStar Vinings Health Park

Smyrna, Georgia, 30080, United States
Wellstar Kennestone Hospital

Marietta, Georgia, 30060, United States
West Michigan Cancer Center

Kalamazoo, Michigan, 49007, United States
West Penn Hospital

Pittsburgh, Pennsylvania, 15224, United States
West Virginia University Charleston Division

Charleston, West Virginia, 25304, United States
West Virginia University Healthcare

Morgantown, West Virginia, 26506, United States
Westchester Medical Center

Valhalla, New York, 10595, United States
Wexford Health and Wellness Pavilion

Wexford, Pennsylvania, 15090, United States
Woman's Hospital

Baton Rouge, Louisiana, 70817, United States
Women and Infants Hospital

Providence, Rhode Island, 02905, United States
Women's Diagnostic Center - Munster

Munster, Indiana, 46321, United States
Yale University

New Haven, Connecticut, 06520, United States
Yale-New Haven Hospital North Haven Medical Center

North Haven, Connecticut, 06473, United States
Yonsei University Health System-Severance Hospital

Seoul, 120-752, South Korea
Zuckerberg San Francisco General Hospital

San Francisco, California, 94110, United States

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