End-stage renal disease (ESRD)
Clinical trials for End-stage renal disease (ESRD) explained in plain language.
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New graft aims to make dialysis easier for kidney patients
Disease control Not yet recruitingThis trial tests a new type of vascular graft, called STARgraft, for people with end-stage kidney disease who need hemodialysis. The graft is placed in the arm to create a reliable access point for dialysis. The study compares STARgraft to a standard graft to see if it works bett…
Matched conditions: END-STAGE RENAL DISEASE (ESRD)
Sponsor: Healionics Corporation • Aim: Disease control
Last updated Aug 15, 2026 00:00 UTC
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Pill vs. machine: which fixes acid imbalance better for dialysis patients?
Disease control Not yet recruitingThis study tests two common methods to treat metabolic acidosis—a condition where blood becomes too acidic—in people on long-term hemodialysis for kidney failure. One group takes oral sodium bicarbonate capsules, while the other gets a higher bicarbonate concentration in their di…
Matched conditions: END-STAGE RENAL DISEASE (ESRD)
Sponsor: University of Sfax • Aim: Disease control
Last updated Jul 23, 2026 00:00 UTC
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Dentist's deep clean may delay dialysis for kidney patients
Disease control Not yet recruitingThis study tests whether a deep dental cleaning (subgingival instrumentation) can slow the progression of chronic kidney disease in 40 adults with diabetes and stage IV-V kidney disease. The cleaning aims to reduce inflammation that may worsen kidney function. Researchers will me…
Matched conditions: END-STAGE RENAL DISEASE (ESRD)
Sponsor: Postgraduate Institute of Dental Sciences Rohtak • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Dialysis fluid removal trial aims to ease heart strain
Disease control Not yet recruitingThis study tests whether adding extra ultrafiltration (a gentle fluid-removal procedure) for 4 or 8 weeks can safely reduce excess fluid in people on hemodialysis. The goal is to lower high blood pressure and relieve symptoms like congestion. About 120 adults with end-stage kidne…
Matched conditions: END-STAGE RENAL DISEASE (ESRD)
Sponsor: University of Washington • Aim: Disease control
Last updated Jun 27, 2026 13:05 UTC
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A protein clue may spot dialysis membrane failure before it starts
Diagnosis Not yet recruitingPeritoneal dialysis uses the belly lining as a natural filter for people with kidney failure, but over time this membrane can scar and stop working. This study tests whether levels of a protein called DKK3 in blood, urine, and dialysis fluid can serve as an early warning sign of …
Matched conditions: END-STAGE RENAL DISEASE (ESRD)
Sponsor: Universität des Saarlandes • Aim: Diagnosis
Last updated Sep 10, 2026 00:00 UTC
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Could an arthritis drug fix Post-Surgery blood sugar crashes?
Symptom relief Not yet recruitingThis study tests whether Anakinra, a drug that reduces inflammation, can prevent dangerous drops in blood sugar after meals in a patient who had his stomach removed. The 52-year-old man also has kidney failure and needs dialysis. Over 10 weeks, he will receive either Anakinra or …
Matched conditions: END-STAGE RENAL DISEASE (ESRD)
Phase 2 • Sponsor: Marc Donath • Aim: Symptom relief
Last updated Jun 27, 2026 12:31 UTC
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Can shorter dialysis sessions still clean the blood effectively?
Knowledge-focused Not yet recruitingThis study tests whether shorter or standard-length dialysis sessions using expanded hemodialysis can remove waste products from the blood as well as a more intensive technique called high-volume hemodiafiltration. Fifteen adults with end-stage kidney disease will try three diffe…
Matched conditions: END-STAGE RENAL DISEASE (ESRD)
Sponsor: Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Hidden TB threat in dialysis patients: new study to reveal true numbers
Knowledge-focused Not yet recruitingThis study will test 200 adults on regular hemodialysis at Sohag University Hospital for latent tuberculosis infection (LTBI) using a simple skin test. The goal is to find out how many dialysis patients carry the bacteria without symptoms, so doctors can better prevent active TB …
Matched conditions: END-STAGE RENAL DISEASE (ESRD)
Sponsor: Sohag University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC