END-STAGE RENAL DISEASE (ESRD)

This study follows 150 adults with end-stage kidney disease who need a hemodialysis graft. The EndoForce System, already approved by the FDA, connects the graft to a vein. Researchers will track safety issues like infections or bleeding, and how well the graft works over time. Th…

This study tests whether a smartphone app and WeChat can help people on long-term dialysis manage their health better. About 392 adults with end-stage kidney disease will either get standard care or extra support through the app, including diet tips, exercise guidance, and medica…

This study looks at whether a plant-focused diet can help malnourished adults on peritoneal dialysis (a type of kidney treatment) improve their nutrition and overall health. About 100 participants will be randomly assigned to either a plant-focused diet or a standard kidney diet …

This study tests a new device called the InnAVasc graft, which is placed under the skin to connect an artery and a vein for easy dialysis access. About 133 adults with end-stage kidney disease will receive the graft and be followed for 2 years. The main goals are to see if the gr…

This study tests a new device that creates a connection between an artery and a vein using a small needle puncture instead of open surgery. The goal is to provide a reliable access point for dialysis in people with kidney failure. About 126 adults will be enrolled and followed fo…

This study compares doing physical therapy during dialysis sessions versus before them in 72 adults with end-stage kidney disease. The goal is to see which timing better improves physical function, quality of life, and blood markers like hemoglobin. Participants will exercise twi…

This study looks at a rare but serious condition called calciphylaxis, where small blood vessels in the skin harden, often leading to death. Researchers will compare 860 adults with chronic kidney disease—some who have calciphylaxis and some who don't—to find clues about what cau…

This study looks at whether adjusting magnesium levels in the dialysis fluid can reduce harmful inflammation and blood cell activation in people with end-stage kidney disease. Fifteen patients will have their dialysis fluid changed in different ways, and researchers will collect …

This study looks at whether making changes at hospitals and dialysis centers can help more people with kidney failure start the process to get a transplant. About 14,000 patients at five large transplant centers will be included. The goal is to see if these changes lead to more p…