DILATED CARDIOMYOPATHY (DCM)
Clinical trials for DILATED CARDIOMYOPATHY (DCM) explained in plain language.
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Second shot of smart cells aims to rescue failing hearts
Disease control Not yet recruitingThis early-stage trial tests whether a second infusion of a patient's own modified immune cells (CAR-DC) can safely improve heart function in people with end-stage dilated cardiomyopathy. The cells target a protein called FAP to calm harmful inflammation. Only 5 adults who previo…
Matched conditions: DILATED CARDIOMYOPATHY (DCM)
Phase: PHASE1 • Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University • Aim: Disease control
Last updated May 26, 2026 05:41 UTC
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Gene therapy trial hopes to strengthen hearts in rare genetic disease
Disease control Not yet recruitingThis early-stage trial tests a single infusion of AFTX-201, a gene therapy designed to help heart muscle cells produce a missing protein in people with dilated cardiomyopathy caused by a BAG3 gene mutation. About 22 adults with moderate heart failure will be enrolled to check saf…
Matched conditions: DILATED CARDIOMYOPATHY (DCM)
Phase: PHASE1, PHASE2 • Sponsor: Affinia Therapeutics • Aim: Disease control
Last updated May 26, 2026 05:35 UTC
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Heart cells grown in lab injected into failing hearts in new trial
Disease control Not yet recruitingThis early-stage trial tests a new treatment for people with severe heart failure. Doctors will inject heart muscle cells grown from stem cells directly into the heart. The goal is to see if it is safe and can help the heart pump better. The study involves 14 participants and fol…
Matched conditions: DILATED CARDIOMYOPATHY (DCM)
Phase: PHASE1, PHASE2 • Sponsor: Heartseed Inc. • Aim: Disease control
Last updated May 26, 2026 04:36 UTC
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New study tracks rare genetic heart condition to unlock clues
Knowledge-focused Not yet recruitingThis study observes 30 adults with dilated cardiomyopathy (a weakened heart muscle) caused by changes in the BAG3 gene. Researchers will track heart function, symptoms, and health outcomes over time to better understand how the disease progresses. No treatment is given—the goal i…
Matched conditions: DILATED CARDIOMYOPATHY (DCM)
Sponsor: Rocket Pharmaceuticals Inc. • Aim: Knowledge-focused
Last updated May 18, 2026 12:11 UTC