DIFFUSE LARGE B-CELL LYMPHOMA
Clinical trials for DIFFUSE LARGE B-CELL LYMPHOMA explained in plain language.
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Smart radiation boosts lymphoma treatment in new trial
Disease control Not yet recruitingThis study tests a personalized approach for people with newly diagnosed diffuse large B-cell lymphoma. After two cycles of standard chemoimmunotherapy, a blood test checks for leftover cancer DNA. If found, patients get low-dose radiation to those spots alongside their regular t…
Matched conditions: DIFFUSE LARGE B-CELL LYMPHOMA
Phase: PHASE2 • Sponsor: University of Nebraska • Aim: Disease control
Last updated May 26, 2026 03:20 UTC
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Experimental NK cell cocktail aims to outsmart resistant lymphoma
Disease control Not yet recruitingThis early-phase trial tests a combination of two antibody drugs (rituximab and tafasitamab) plus donated natural killer (NK) immune cells for people with B-cell non-Hodgkin lymphoma that has returned or not responded to at least two prior treatments. Up to 15 participants will r…
Matched conditions: DIFFUSE LARGE B-CELL LYMPHOMA
Phase: PHASE1 • Sponsor: Paolo Caimi, MD • Aim: Disease control
Last updated May 26, 2026 03:20 UTC
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Radiation plus immune therapy combo tested for hard-to-treat lymphoma
Disease control Not yet recruitingThis early-phase study tests whether giving radiation therapy before a type of immunotherapy (bispecific antibodies) is safe for people with diffuse large B-cell lymphoma that has come back or not responded to at least two prior treatments. The study will enroll 12 adults and foc…
Matched conditions: DIFFUSE LARGE B-CELL LYMPHOMA
Phase: PHASE1 • Sponsor: University of Utah • Aim: Disease control
Last updated May 26, 2026 03:16 UTC
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New CAR-T therapy aims to tackle tough lymphoma in early trial
Disease control Not yet recruitingThis early-phase study tests a new treatment called CY-219 CAR-T cells for people with B-cell lymphoma that has come back or not responded to standard therapy. The treatment involves modifying the patient's own immune cells to better recognize and attack cancer cells. The main go…
Matched conditions: DIFFUSE LARGE B-CELL LYMPHOMA
Phase: PHASE1 • Sponsor: Institute of Hematology & Blood Diseases Hospital, China • Aim: Disease control
Last updated May 26, 2026 03:13 UTC
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New drug trio aims to replace chemo for aggressive lymphoma
Disease control Not yet recruitingThis study tests a combination of three targeted drugs (polatuzumab vedotin, glofitamab, and tafasitamab) as a first treatment for people with aggressive B-cell lymphomas. The goal is to see if this chemo-free approach can shrink tumors effectively while causing fewer side effect…
Matched conditions: DIFFUSE LARGE B-CELL LYMPHOMA
Phase: PHASE2 • Sponsor: Brown University • Aim: Disease control
Last updated May 26, 2026 03:12 UTC
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New drug aims to wipe out lingering lymphoma cells after remission
Disease control Not yet recruitingThis study tests a drug called chidamide in people with a type of lymphoma (double-expressor DLBCL) who are in remission after initial treatment but still have tiny amounts of cancer DNA in their blood. The goal is to see if taking chidamide pills can clear this hidden disease an…
Matched conditions: DIFFUSE LARGE B-CELL LYMPHOMA
Phase: PHASE2 • Sponsor: Rong Tao • Aim: Disease control
Last updated May 20, 2026 11:53 UTC
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New hope for tough lymphoma: drug cocktail targets resistant cancer
Disease control Not yet recruitingThis study tests a new combination of drugs (homoharringtonine, a BCL-2 inhibitor, rituximab, and prednisone) in adults whose diffuse large B-cell lymphoma has come back or not responded to standard treatment. The goal is to find the safest dose and see if the combination shrinks…
Matched conditions: DIFFUSE LARGE B-CELL LYMPHOMA
Phase: PHASE1, PHASE2 • Sponsor: First Affiliated Hospital of Zhejiang University • Aim: Disease control
Last updated May 18, 2026 12:03 UTC
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Elderly lymphoma patients may get better quality of life with Geriatric-Guided care
Symptom relief Not yet recruitingThis study looks at whether adding a geriatric-guided care plan—including nutrition, physical, and social support—to standard cancer treatment can improve quality of life for older adults (70+) with diffuse large B-cell lymphoma. About 170 participants will be assigned to either …
Matched conditions: DIFFUSE LARGE B-CELL LYMPHOMA
Phase: NA • Sponsor: Fondazione Italiana Linfomi - ETS • Aim: Symptom relief
Last updated May 22, 2026 14:03 UTC