Dialysis; complications

This study looks at whether a lower dose of continuous dialysis (CRRT) is safe and works as well as the standard dose for critically ill patients with acute kidney failure in the ICU. About 100 adults who need dialysis will be randomly assigned to receive either the standard dose…

This study compares starting dialysis twice a week versus the standard three times a week in elderly patients (60+) with end-stage kidney disease who still produce some urine. The goal is to see if fewer sessions reduce hospitalizations, falls, and other complications while maint…

This study tests a device that helps people on dialysis get needles into their fistula more easily. It is for patients whose fistula is too deep for standard needle sticks. The study will check if the device works well and is safe over 6 to 12 months. About 100 adults will take p…

This study tests a new drug called pegmolesatide, alone or combined with roxadustat, to treat anemia in 240 adults on dialysis for chronic kidney disease. Participants currently on another anemia drug (rHuEPO) will switch to one of three treatment plans for 24 weeks. The goal is …

This study tests whether a specific physical activity program, called the GH Method, can improve physical abilities in people who are frail and on dialysis or have advanced kidney disease. Participants attend two one-hour muscle therapy sessions per week for 12 months. Researcher…

Acute kidney injury affects half of ICU patients, often requiring dialysis. This study compares a lower dose of dialysis to the standard dose in 20 critically ill adults. The goal is to see if the lower dose is safe and effective, and to inform a larger future trial.

This study reviews medical records from over 50,000 critically ill patients to see if starting dialysis earlier helps them live longer. Researchers will compare patients who started dialysis early versus late, looking at survival up to 90 days and beyond. The goal is to find the …