DIABETIC MACULAR EDEMA (DME)
Clinical trials for DIABETIC MACULAR EDEMA (DME) explained in plain language.
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First-in-Human trial tests novel injection to fight diabetic vision loss
Disease control Recruiting nowThis is an early-stage study to check if a new drug called avoralstat is safe when injected into the eye of people with diabetic macular edema (DME), a condition that causes vision loss. The study will enroll 9 adults with DME to receive a single injection at one of three dose le…
Matched conditions: DIABETIC MACULAR EDEMA (DME)
Phase: PHASE1 • Sponsor: BioCryst Pharmaceuticals • Aim: Disease control
Last updated Apr 03, 2026 14:42 UTC
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New eye implant could drastically reduce injections for diabetic vision loss
Disease control Recruiting nowThis study is testing a new, long-acting eye implant called EYP-1901 against the standard aflibercept injections for diabetic macular edema (DME), a common cause of vision loss in people with diabetes. The main goal is to see if the implant can control the disease just as well wh…
Matched conditions: DIABETIC MACULAR EDEMA (DME)
Phase: PHASE3 • Sponsor: EyePoint Pharmaceuticals, Inc. • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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New eye implant could drastically reduce injections for diabetic vision loss
Disease control Recruiting nowThis study is testing if a new, long-acting eye implant called EYP-1901 can control vision loss from diabetic macular edema as well as standard aflibercept injections, but with far fewer treatments. It will involve about 240 adults with the condition, comparing the implant's effe…
Matched conditions: DIABETIC MACULAR EDEMA (DME)
Phase: PHASE3 • Sponsor: EyePoint Pharmaceuticals, Inc. • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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Gene therapy trial offers hope for diabetic eye disease
Disease control Recruiting nowThis early-stage study is testing a new gene therapy called LX111 for diabetic macular edema, a vision-threatening complication of diabetes. Researchers will give a single injection into the eye to 32 participants who have previously responded to standard anti-VEGF treatments. Th…
Matched conditions: DIABETIC MACULAR EDEMA (DME)
Phase: EARLY_PHASE1 • Sponsor: Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine • Aim: Disease control
Last updated Mar 23, 2026 15:19 UTC
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New eye gel aims to take the sting out of Vision-Saving injections
Symptom relief Recruiting nowThis study is testing if a new numbing gel (chloroprocaine) works as well as the current standard method (eye drops plus a small injection) to reduce pain during eye injections for conditions like macular degeneration and diabetic eye disease. About 236 adults who regularly get t…
Matched conditions: DIABETIC MACULAR EDEMA (DME)
Phase: PHASE4 • Sponsor: Harrow Inc • Aim: Symptom relief
Last updated Apr 02, 2026 14:57 UTC