Diabetic macular edema (DME)
Clinical trials for Diabetic macular edema (DME) explained in plain language.
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Can a new eye injection beat the current standard for diabetic vision loss?
Disease control Recruiting nowThis phase 3 trial compares an experimental drug, tabirafusp tedromer, against the standard treatment aflibercept for people with diabetic macular edema (DME), a leading cause of vision loss in diabetes. About 910 adults with DME will receive injections into the eye and be follow…
Matched conditions: DIABETIC MACULAR EDEMA (DME)
Phase 3 • Sponsor: Kodiak Sciences Inc • Aim: Disease control
Last updated Aug 23, 2026 00:00 UTC
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New hope for diabetes-related vision loss: experimental drug faces final test
Disease control Recruiting nowThis study tests a new eye medication called BAT5906 against an approved drug (Lucentis) for people with diabetic macular edema, a condition that causes vision loss in diabetes. About 406 adults with type 1 or type 2 diabetes will receive injections into the eye and be followed f…
Matched conditions: DIABETIC MACULAR EDEMA (DME)
Phase 3 • Sponsor: Bio-Thera Solutions • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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Gene therapy injection aims to ease diabetic eye swelling
Disease control Recruiting nowThis early-phase study tests a gene therapy called LX111 for diabetic macular edema (DME), a condition that causes vision loss due to swelling in the retina. About 32 adults with DME will receive a single injection into the eye. The main goals are to check safety and see if it he…
Matched conditions: DIABETIC MACULAR EDEMA (DME)
Early phase 1 • Sponsor: Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Could a pill replace eye injections for diabetic vision loss?
Symptom relief Recruiting nowResearchers are testing an experimental oral drug called BGE-102 in adults with diabetic macular edema, a condition where fluid leaks into the center of the retina and blurs vision. The trial enrolls about 180 people with type 1 or type 2 diabetes and center-involved DME. Partici…
Matched conditions: DIABETIC MACULAR EDEMA (DME)
Phase 2 • Sponsor: BioAge Labs, Inc. • Aim: Symptom relief
Last updated Sep 12, 2026 00:00 UTC
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Eye scan showdown: faricimab vs ranibizumab in diabetic retinopathy
Knowledge-focused Recruiting nowThis study compares two eye injections—faricimab and a biosimilar version of ranibizumab—in 100 adults with diabetic retinopathy. Researchers will use eye scans (OCT and OCT angiography) to see which drug leads to better early changes in the retina after three monthly doses. The …
Matched conditions: DIABETIC MACULAR EDEMA (DME)
Sponsor: Osijek University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC