DIABETIC KIDNEY DISEASE

This study tests whether pentoxifylline, a medication used since 1984 for leg blood vessel problems, can slow kidney damage and delay death in people with diabetic kidney disease. About 2,376 participants from 40 VA hospitals are taking part. The goal is to see if this drug can p…

This study was designed to test an experimental drug called VAR200 in adults with type 2 diabetes and kidney disease. The goal was to see if the drug could reduce protein in the urine, a sign of kidney damage, and to check for side effects. However, the trial was withdrawn before…

This study looks at two ways of doing peritoneal dialysis (a treatment for kidney failure) in 100 new patients. One method uses a standard full dose, while the other uses a smaller, tailored dose based on how much kidney function remains. The goal is to see which approach better …

This study aims to understand why some people with diabetes develop kidney disease, especially in Ecuador. Researchers will look at social, environmental, and biological factors in over 10,000 adults, including those with and without diabetes or kidney problems. The goal is to fi…

This study looks at why many people with type 1 diabetes still develop kidney disease, even with modern glucose monitors and insulin pumps. Researchers will use kidney biopsies and advanced imaging to find hidden risk factors like insulin resistance and inflammation. The goal is …

This study is creating a large biobank of 48,000 people with diabetes in Hong Kong. Researchers will collect blood samples and health data to find genetic markers that predict serious complications like kidney failure, heart disease, and stroke. The goal is to improve early detec…

This study looks at American Indians with type 2 diabetes who have kidney problems. Researchers want to see if a past treatment with the drug losartan still helps protect their kidneys years later. Participants will have tests like blood and urine samples, and some will get a kid…

This study looks at how certain immune proteins, called the complement system, may make kidney disease worse in people with diabetes. Researchers will measure these proteins in blood and urine from 90 participants to see if they are linked to kidney damage and blood vessel health…

This study looks at the DNA of over 9,000 people with diabetes and kidney disease, along with their family members, to find genes that increase the risk of diabetic kidney disease. Researchers are collecting blood samples and health information to identify genetic markers. The go…