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Depressive disorders
Clinical trials for Depressive disorders explained in plain language.
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Can a diabetes drug beat metformin for antipsychotic weight gain?
Disease control Not yet recruitingThis study compares dapagliflozin and metformin for managing weight gain caused by antipsychotic medications. About 110 adults aged 16 and older will take one of the drugs plus lifestyle advice for 26 weeks. The goal is to see which drug works better and is safer for weight contr…
Matched conditions: DEPRESSIVE DISORDERS
Phase 4 • Sponsor: Sultan Qaboos University • Aim: Disease control
Last updated Jun 27, 2026 13:07 UTC
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Bright light, better mood? glasses that mimic morning sun tested for depression on dialysis
Symptom relief Not yet recruitingThis trial tests whether light therapy glasses can reduce depression in people with end-stage kidney disease who undergo hemodialysis three times a week. Participants wear either active glasses (1000 lux) or a sham device (50 lux) for 30 minutes each session over five weeks. The …
Matched conditions: DEPRESSIVE DISORDERS
Sponsor: Centre Hospitalier Annecy Genevois • Aim: Symptom relief
Last updated Aug 19, 2026 00:00 UTC
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Could a blood test unlock the biology of depression?
Knowledge-focused Not yet recruitingThis study investigates whether certain chemicals in the blood, called kynurenine metabolites, are linked to depressive disorders. Researchers will compare 45 people with depression to 45 healthy individuals, all aged 18 to 60. Participants will undergo psychological assessments …
Matched conditions: DEPRESSIVE DISORDERS
Sponsor: Sohag University • Aim: Knowledge-focused
Last updated Aug 22, 2026 00:00 UTC