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Bright light, better mood? glasses that mimic morning sun tested for depression on dialysis

NCT ID NCT07729358

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 27, 2026 · Last updated Aug 18, 2026 · Updated 3 times

Summary

This trial tests whether light therapy glasses can reduce depression in people with end-stage kidney disease who undergo hemodialysis three times a week. Participants wear either active glasses (1000 lux) or a sham device (50 lux) for 30 minutes each session over five weeks. The goal is to see if morning light exposure improves mood and sleep quality without medication.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
light therapy using active glasses (Luminette3) emitting 1000 lux
What this could lead to
If effective, light therapy could offer a drug-free way to ease depression and improve sleep in people undergoing kidney dialysis.
What could go wrong
This is a relatively small, early-stage trial. The sham device also emits some light (50 lux), which may reduce the difference between groups. Light therapy may not work for everyone and requires consistent use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 340 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Dec 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patient informed about the nature, process, and objectives of the study and having signed a free and informed consent to participate, * Patient treated with conventional hemodialysis for at least 3 months and currently undergoing dialysis 3 times a week, * Patient covered by the french national social welfare Non-Inclusion Criteria: * Patient who has initiated or modified antidepressive treatment within the 4 weeks prior to the inclusion visit, * Patient with initiation of antidepressive treatment within the 10 weeks following the inclusion visit (screening and intervention periods), * Patient who has initiated or modified anxiolytic, hypnotic, or melatonin treatment within the 4 weeks prior to the inclusion visit, * Patient presenting with binocular blindness or age-related macular degeneration (AMD), * Patient receiving medical and/or surgical treatment for a retinal condition, * Patient who has undergone ocular surgery within the 12 weeks prior to the inclusion visit, * Patient scheduled for ocular surgery within the 10 weeks following the inclusion visit (screening and intervention periods), * Patient suffering from neurocognitive disorders, schizophrenia or other primary psychotic disorders, or bipolar disorder or related conditions, * Pregnant or breastfeeding patient, * Patient unable to understand the French language both orally and in writing, making self-assessment impossible, * Patient currently participating in another interventional research protocol, except for the IDE-3D protocol (RIPH2) conducted by the CH Annecy Genevois, * Patient who has already been randomized in the present study, * Patient under guardianship, curatorship, or placed under judicial protection. Randomisation criteria The patient will be considered eligible for randomization if they have a HADS-D screening score dated within a maximum of 15 days and meet one of the following two criteria: * HADS-D screening score ≥ 8 and \< 15, * HADS-D screening score ≥ 15, provided that a medical follow-up assessment has been conducted following this diagnosis during the screening period, and that it does not lead to the recommendation for the initiation or modification of antidepressant treatment and/or psychotherapy within the 10 weeks following the inclusion visit (screening and intervention periods).

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Centre Hospitalier Annecy Genevois

    Annecy, 74370, France

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