DEPRESSIVE DISORDER, TREATMENT-RESISTANT
Clinical trials for DEPRESSIVE DISORDER, TREATMENT-RESISTANT explained in plain language.
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Brain zapping gets a GPS upgrade: study aims to boost depression relief
Symptom relief OngoingThis study tests whether using MRI scans to guide a noninvasive brain-stimulation treatment (rTMS) works better than the usual scalp-based method for people with depression. About 54 veterans will participate. The goal is to improve functioning and quality of life. For those with…
Matched conditions: DEPRESSIVE DISORDER, TREATMENT-RESISTANT
Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated May 26, 2026 08:34 UTC
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Zapped away sadness? brain stimulation trial for tough depression pulled
Symptom relief TerminatedThis study aimed to see if a mild electrical brain stimulation (tDCS) could help people with severe depression that didn't improve after at least five treatments. Participants would have received 30 sessions over six weeks, either real or fake stimulation, alongside their usual c…
Matched conditions: DEPRESSIVE DISORDER, TREATMENT-RESISTANT
Phase: NA • Sponsor: University of Alberta • Aim: Symptom relief
Last updated May 20, 2026 11:56 UTC
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Dopamine drug may lift brain fog and slow steps in elderly depression
Symptom relief OngoingThis study looks at whether a drug that increases dopamine (carbidopa/levodopa) can improve thinking speed, walking, and mood in older adults with depression. About 100 people aged 60 and older with depression and slow thinking or walking will take the drug or a placebo. The goal…
Matched conditions: DEPRESSIVE DISORDER, TREATMENT-RESISTANT
Phase: PHASE2 • Sponsor: Vanderbilt University Medical Center • Aim: Symptom relief
Last updated May 12, 2026 13:42 UTC