Coronary microvascular dysfunction
Clinical trials for Coronary microvascular dysfunction explained in plain language.
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New device aims to unclog the Heart's drain for stubborn heart failure patients
Disease control By invitation onlyThis study tests a small device, called the Coronary Sinus Reducer, in 35 people with a type of heart failure where the heart pumps well but still has trouble filling with blood. The device is placed in a vein of the heart to help lower pressure during exercise. The goal is to se…
Matched conditions: CORONARY MICROVASCULAR DYSFUNCTION
Sponsor: Mayo Clinic • Aim: Disease control
Last updated Aug 07, 2026 00:00 UTC
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New heart device aims to quiet chest pain in Hard-to-Treat condition
Symptom relief OngoingThis study tests a new device called the A-FLUX Coronary Sinus Reducer to see if it can safely improve chest pain or discomfort in people with coronary microvascular dysfunction (CMD), a condition where tiny heart vessels don't work properly. About 30 adults with persistent sympt…
Matched conditions: CORONARY MICROVASCULAR DYSFUNCTION
Sponsor: VahatiCor, Inc. • Aim: Symptom relief
Last updated Aug 28, 2026 00:00 UTC
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Cancer drug heart risk under the microscope
Knowledge-focused By invitation onlyThis study watches 25 people with breast or lung cancer who are getting immune checkpoint inhibitor therapy. Researchers use heart scans and blood tests to see if the treatment harms the heart's tiny blood vessels. No new drugs are given; the goal is to learn how to better protec…
Matched conditions: CORONARY MICROVASCULAR DYSFUNCTION
Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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Mystery chest pain: study digs deeper to find hidden heart problems
Knowledge-focused OngoingThis study involves 500 people who have chest pain or other signs of heart trouble, but whose main heart arteries are not blocked. Researchers use special tools during a heart catheterization to measure tiny blood vessel function and look for hidden causes like microvascular dise…
Matched conditions: CORONARY MICROVASCULAR DYSFUNCTION
Sponsor: Yale University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC