Coronary microvascular disease

This study tests whether a 36-session cardiac rehabilitation program (exercise plus education) can improve quality of life in people with coronary microvascular disease, a condition where small heart vessels don't work properly. About 204 participants with angina and confirmed mi…

This study tests a device called a coronary sinus reducer in 50 people with chest pain caused by coronary microvascular disease, a condition where small heart vessels don't work properly. The device is implanted to narrow a heart vein, which may improve blood flow. Half the parti…

This trial is testing whether a new PET imaging tracer, 18F-flurpiridaz, can detect coronary artery disease as accurately as the current standard, 82Rb-chloride. The study will involve 60 adults scheduled for a clinically indicated PET scan. Researchers will compare the diagnosti…

This study tests a new device called the A-FLUX Coronary Sinus Reducer to see if it can safely improve chest pain or discomfort in people with coronary microvascular dysfunction (CMD), a condition where tiny heart vessels don't work properly. About 30 adults with persistent sympt…

This study is a registry that follows over 1,000 people with suspected ischemic heart disease. Doctors use special tests during heart catheterization to measure blood flow and pressure in the heart's small vessels. The goal is to see if these measurements can predict future heart…

This registry follows over 670 people with chest pain and non-blocked arteries to study how well tiny heart vessels (microcirculation) work. Participants complete questionnaires about their symptoms and are tracked for up to 5 years for heart events like heart attacks or strokes.…

This study looks at why some women with chest pain or signs of heart disease have normal-looking large arteries but still have problems with tiny blood vessels in the heart. Researchers will measure platelet activity and inflammation during a heart catheterization to see if these…