CONTINUOUS RENAL REPLACEMENT THERAPY (CRRT)

This study tests a newer blood thinner, nafamostat mesylate, against the standard citrate for patients with sepsis and severe kidney injury who need continuous dialysis. The goal is to see if the newer drug works just as well or better at preventing death, ongoing kidney failure,…

This study looks at whether giving more protein (1.5-1.7 grams per kilogram per day) to critically ill patients with acute kidney injury on continuous dialysis can reduce muscle wasting compared to standard protein intake (1.0-1.2 grams per kilogram per day). About 56 adults will…

This study compares a new ultrasound-based method (mVExUS) to standard care for guiding how much fluid to remove during dialysis in critically ill patients with acute kidney injury. About 126 adults in the ICU will be randomly assigned to either method, with fluid checks every 8 …

This study will collect information from up to 100,000 critically ill patients in intensive care units (ICUs) around the world who receive continuous kidney dialysis (CRRT). The goal is to understand how different hospitals use this treatment and how it affects patient outcomes. …

This study looks at whether a permanent arteriovenous access (fistula or graft) can be safely used for continuous kidney replacement therapy in ICU patients with end-stage kidney disease. Currently, catheters are used most often, but they raise risks of infection and vein damage.…