Massive global registry aims to unlock secrets of ICU dialysis
NCT ID NCT07365111
First seen Jun 25, 2026 · Last updated Sep 10, 2026 · Updated 3 times
Summary
This study will collect information from 100,000 critically ill patients worldwide who receive continuous renal replacement therapy (CRRT), a type of kidney dialysis, in intensive care units. Researchers want to understand how CRRT is used and how it affects patient survival and kidney recovery. The goal is to find better ways to deliver this life-saving treatment.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this registry could reveal best practices for CRRT, potentially improving survival and kidney recovery in critically ill patients.
- What could go wrong
- This is an observational study, not a treatment trial. It cannot prove what works best, only describe current practices. Results may not apply to all ICUs.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 100,000 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Mar 2027
An estimate. Start dates often move.
- Expected to finish
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Dec 2036
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients with new acute kidney injury and initiation of continuous renal replacement therapy who are admitted to an intensive care unit and who have received continuous renal replacement therapy for at least 24 hours will be eligible for this study.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Admission to an intensive care unit 2. CRRT therapy Exclusion Criteria: 1. End-stage kidney disease 2. CRRT \<24 hours
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of Alberta
Edmonton, Alberta, T6G 2G3, Canada
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