Colorectal neoplasms malignant
Clinical trials for Colorectal neoplasms malignant explained in plain language.
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Can a four-drug cocktail shrink hard-to-treat colorectal cancer?
Disease control Recruiting nowThis phase 2 trial is testing whether adding two extra drugs—bevacizumab and sintilimab—to the usual combination of irinotecan and cetuximab can shrink tumors in people with advanced colorectal cancer that no longer responds to irinotecan. The study enrolls 160 adults with RAS wi…
Matched conditions: COLORECTAL NEOPLASMS MALIGNANT
Phase 2 • Sponsor: Guangdong Provincial People's Hospital • Aim: Disease control
Last updated Sep 18, 2026 00:00 UTC
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Could a wait-and-see approach replace chemo for lung metastases in colorectal cancer?
Disease control Recruiting nowThis study looks at colorectal cancer patients whose disease is under control (no evidence of disease) but later develop a small number of lung tumors. Instead of starting chemotherapy right away, doctors will treat the lung spots with surgery or radiation and then watch closely.…
Matched conditions: COLORECTAL NEOPLASMS MALIGNANT
Phase 2 • Sponsor: Shandong Cancer Hospital and Institute • Aim: Disease control
Last updated Jun 27, 2026 12:25 UTC
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New blood test could spot colon cancer before it spreads
Diagnosis Recruiting nowThis study is testing a new blood test called DENEB that looks for tiny molecules (microRNAs) to find colorectal cancer and precancerous polyps early. Researchers will collect blood samples from 2,000 people who are also getting a colonoscopy. The goal is to see if the blood test…
Matched conditions: COLORECTAL NEOPLASMS MALIGNANT
Sponsor: City of Hope Medical Center • Aim: Diagnosis
Last updated Jul 09, 2026 00:00 UTC
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New blood test could spot colon cancer in young adults before It's too late
Diagnosis Recruiting nowThis study is developing a blood test that uses tiny particles called exosomes and machine learning to detect colorectal cancer in people under 50. The test looks for specific microRNA patterns in the blood. Researchers will compare results from 400 people—some with cancer and so…
Matched conditions: COLORECTAL NEOPLASMS MALIGNANT
Sponsor: City of Hope Medical Center • Aim: Diagnosis
Last updated Jul 09, 2026 00:00 UTC