CNS TUMOR
Clinical trials for CNS TUMOR explained in plain language.
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New hope for toddlers with rare brain tumors: targeted pill may shrink tumors without chemo
Disease control Recruiting nowThis study tests a drug called entrectinib for children under 3 with specific types of brain tumors (NTRK or ROS1-fused). The drug targets the genetic changes driving the tumor, aiming to shrink it and delay growth. About 52 children will receive the drug alone, avoiding traditio…
Matched conditions: CNS TUMOR
Phase: PHASE2 • Sponsor: St. Jude Children's Research Hospital • Aim: Disease control
Last updated May 26, 2026 06:47 UTC
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New hope for kids with deadly brain tumors: experimental drug ONC206 enters human testing
Disease control Recruiting nowThis study tests an experimental drug called ONC206 in children and young adults with a type of brain tumor called diffuse midline glioma (DMG) or other recurring brain cancers. The drug works by causing stress in cancer cells, making them die without harming healthy cells. The g…
Matched conditions: CNS TUMOR
Phase: PHASE1 • Sponsor: Sabine Mueller, MD, PhD • Aim: Disease control
Last updated May 20, 2026 11:56 UTC
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New hope for Hard-to-Treat cancers: first human trial launches
Disease control Recruiting nowThis early-stage study tests a new drug called PHST001, alone or with chemotherapy, in adults with advanced solid tumors that have stopped responding to standard treatments. The main goals are to check safety and find the best dose. About 272 people with cancers like ovarian, end…
Matched conditions: CNS TUMOR
Phase: PHASE1 • Sponsor: Pheast Therapeutics • Aim: Disease control
Last updated May 19, 2026 11:47 UTC
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Phone app could replace some In-Person brain tumor exams
Knowledge-focused Recruiting nowThis study is testing a mobile app called Iskhaa that lets brain tumor patients do neurological exams at home. About 600 people aged 5 and older will use the app to record videos of tasks like walking or speaking. The goal is to see if the app's results match what doctors find du…
Matched conditions: CNS TUMOR
Sponsor: Tata Memorial Centre • Aim: Knowledge-focused
Last updated May 26, 2026 06:50 UTC
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Childhood cancer Survivors' sleep under the microscope
Knowledge-focused Recruiting nowThis study looks at sleep issues in adults who survived childhood cancer, focusing on three groups: those treated for ALL, brain tumors, or solid tumors. Researchers will use questionnaires and home sleep monitors to measure insomnia, sleep quality, and daytime sleepiness. The go…
Matched conditions: CNS TUMOR
Sponsor: St. Jude Children's Research Hospital • Aim: Knowledge-focused
Last updated May 22, 2026 13:51 UTC