CLOSTRIDIUM DIFFICILE INFECTION
Clinical trials for CLOSTRIDIUM DIFFICILE INFECTION explained in plain language.
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Poop transplant plus drug shows promise against recurrent c. diff in IBD patients
Disease control CompletedThis study tested whether adding a drug called bezlotoxumab to a fecal microbiota transplant (FMT) could better prevent repeat Clostridium difficile infections in people with inflammatory bowel disease (IBD). About 61 adults with at least two past C. diff infections took part. Th…
Matched conditions: CLOSTRIDIUM DIFFICILE INFECTION
Phase: PHASE2 • Sponsor: Brigham and Women's Hospital • Aim: Disease control
Last updated May 26, 2026 12:04 UTC
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Dietary change may cut c. diff recurrence in cancer patients
Disease control CompletedThis study looked at whether eating less fat and more fiber can lower the chance of a repeat Clostridioides difficile infection in people being treated for cancer. Eight patients with leukemia, lymphoma, or other cancers who had a recent C. diff infection took part. Researchers t…
Matched conditions: CLOSTRIDIUM DIFFICILE INFECTION
Phase: NA • Sponsor: University of Colorado, Denver • Aim: Disease control
Last updated May 18, 2026 12:09 UTC
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Poop pills? fecal transplant shows promise for gut infection
Disease control CompletedThis study tested a procedure called fecal microbiota transplant (FMT) in 24 adults with recurring Clostridium difficile (C. diff) infection. FMT involves placing healthy donor stool into the patient's colon to restore good bacteria killed by antibiotics. The goal was to see if F…
Matched conditions: CLOSTRIDIUM DIFFICILE INFECTION
Phase: PHASE4 • Sponsor: Methodist Health System • Aim: Disease control
Last updated May 18, 2026 11:58 UTC
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Simple taper strategy may cut c. diff recurrence risk
Prevention CompletedThis study looked at whether giving a gradual, lower dose of vancomycin for two extra weeks after the standard treatment can prevent C. diff infection from coming back. About 263 adults who had their first or second C. diff infection took part. Half received a placebo and half re…
Matched conditions: CLOSTRIDIUM DIFFICILE INFECTION
Phase: PHASE3 • Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre • Aim: Prevention
Last updated May 20, 2026 11:53 UTC
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Should cancer patients get antibiotics for mild c. diff? study investigates
Knowledge-focused CompletedThis study looked at whether giving antibiotics (vancomycin) to cancer patients with a mild form of C. difficile infection helps. The infection was detected by a sensitive test but not confirmed by a toxin test. The study measured changes in C. difficile levels in stool and gut h…
Matched conditions: CLOSTRIDIUM DIFFICILE INFECTION
Phase: PHASE2 • Sponsor: Medical College of Wisconsin • Aim: Knowledge-focused
Last updated May 26, 2026 12:01 UTC