CLINICALLY ISOLATED SYNDROME
Clinical trials for CLINICALLY ISOLATED SYNDROME explained in plain language.
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Early ocrevus treatment may tame MS brain inflammation, small study hints
Disease control OngoingThis study gives ocrelizumab (Ocrevus) to 30 people newly diagnosed with relapsing multiple sclerosis or a first high-risk attack. Researchers measure spinal fluid markers of inflammation before and after 3 years of treatment to see if the drug reduces chronic brain inflammation.…
Matched conditions: CLINICALLY ISOLATED SYNDROME
Phase: PHASE4 • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated Jun 22, 2026 11:55 UTC
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Lifestyle showdown: can diet and exercise replace MS drugs?
Disease control OngoingThis study looks at whether a healthy lifestyle—including diet, stress reduction, and exercise—can control symptoms and improve quality of life for people newly diagnosed with multiple sclerosis (MS) or its early stage, clinically isolated syndrome (CIS). Researchers are comparin…
Matched conditions: CLINICALLY ISOLATED SYNDROME
Phase: NA • Sponsor: Terry L. Wahls • Aim: Disease control
Last updated Jun 10, 2026 13:25 UTC
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AI brain scans could revolutionize MS care
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at whether using an AI tool to analyze brain MRIs helps doctors spot signs of multiple sclerosis (MS) activity more accurately. About 750 people with MS or early warning signs will be split into two groups: one where doctors use the AI tool, and one where they re…
Matched conditions: CLINICALLY ISOLATED SYNDROME
Phase: NA • Sponsor: icometrix • Aim: Knowledge-focused
Last updated Jun 22, 2026 12:05 UTC
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Massive italian study tracks 96,000 MS patients to unlock better care
Knowledge-focused ENROLLING_BY_INVITATIONThis study is creating a large database of up to 96,000 people in Italy with multiple sclerosis (MS) and similar conditions like neuromyelitis optica. Researchers will collect health information over time to understand the diseases better, improve treatment, and guide healthcare …
Matched conditions: CLINICALLY ISOLATED SYNDROME
Sponsor: Fondazione Italiana Sclerosi Multipla • Aim: Knowledge-focused
Last updated Jun 18, 2026 11:46 UTC
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Brain's garbage disposal may be broken in early MS, new MRI study hints
Knowledge-focused OngoingThis study looks at whether the brain's natural waste-cleaning system, called the glymphatic system, is not working properly in people with Clinically Isolated Syndrome (CIS), which is often the first sign of Multiple Sclerosis (MS). Researchers will use special MRI scans to comp…
Matched conditions: CLINICALLY ISOLATED SYNDROME
Sponsor: University of Exeter • Aim: Knowledge-focused
Last updated Jun 17, 2026 12:05 UTC