CLINICAL STAGE II ESOPHAGEAL ADENOCARCINOMA AJCC V8
Clinical trials for CLINICAL STAGE II ESOPHAGEAL ADENOCARCINOMA AJCC V8 explained in plain language.
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New combo aims to boost tumor kill before esophageal cancer surgery
Disease control Recruiting nowThis study tests whether giving a shorter, higher-dose radiation therapy along with the chemotherapy drugs FOLFOX before surgery can kill more tumor cells in people with stage I-III esophageal or gastroesophageal junction cancer. About 99 adults who are candidates for surgery wil…
Matched conditions: CLINICAL STAGE II ESOPHAGEAL ADENOCARCINOMA AJCC V8
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated May 26, 2026 04:35 UTC
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Could a common heart drug boost cancer treatment?
Disease control Recruiting nowThis study tests whether adding propranolol (a beta-blocker used for heart conditions) to standard chemotherapy and immunotherapy (pembrolizumab) can improve treatment for advanced esophageal or gastroesophageal junction cancer that cannot be surgically removed. About 40 adults w…
Matched conditions: CLINICAL STAGE II ESOPHAGEAL ADENOCARCINOMA AJCC V8
Phase: PHASE2 • Sponsor: Roswell Park Cancer Institute • Aim: Disease control
Last updated May 26, 2026 04:34 UTC
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New drug combo shows promise in advanced stomach cancer trial
Disease control Recruiting nowThis study is for people with advanced stomach or esophageal cancer that has spread. It tests whether adding the immunotherapy drug nivolumab to the usual two-drug treatment (paclitaxel and ramucirumab) helps control the cancer longer. About 224 participants will be randomly assi…
Matched conditions: CLINICAL STAGE II ESOPHAGEAL ADENOCARCINOMA AJCC V8
Phase: PHASE2, PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 26, 2026 04:34 UTC
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Radiation-Activated nanoparticles aim to boost esophageal cancer treatment
Disease control Recruiting nowThis early-phase study tests a new drug called NBTXR3, which is injected into the tumor and activated by radiation therapy to destroy cancer cells. It is given alongside standard chemotherapy for people with stage II or III esophageal adenocarcinoma. The main goal is to find the …
Matched conditions: CLINICAL STAGE II ESOPHAGEAL ADENOCARCINOMA AJCC V8
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 22, 2026 13:50 UTC
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New radiation method could spare heart and lungs in esophageal cancer patients
Disease control Recruiting nowThis study compares two radiation techniques for people with stage I to IVA esophageal cancer: proton beam therapy (PBT) and intensity modulated photon radiotherapy (IMRT). The goal is to see which one helps patients live longer and causes fewer serious heart and lung side effect…
Matched conditions: CLINICAL STAGE II ESOPHAGEAL ADENOCARCINOMA AJCC V8
Phase: PHASE3 • Sponsor: NRG Oncology • Aim: Disease control
Last updated May 11, 2026 20:50 UTC