CLAUDICATION

This study is testing a device that uses sound waves (shockwaves) to break up calcium buildup in the leg arteries of people with peripheral artery disease. The goal is to improve blood flow, reduce pain, and help patients walk better. About 50 participants will be followed for on…

This early-stage study tests whether fisetin, a compound found in fruits, can reduce aging-related cells in the body and improve walking ability in 34 people aged 50+ with peripheral artery disease (PAD). Participants will take fisetin or a placebo for several months, and researc…

This study tests whether combining the DASH diet (a heart-healthy eating plan) with a home-based walking program can help people with peripheral artery disease (PAD) walk longer and feel better. About 150 adults with PAD and leg cramps will follow the program for 3 months. The go…

This study looks at whether the natural pulsation of the spinal cord lining (dura) is linked to pain and disability in people with lumbar spinal stenosis, a condition where the spinal canal narrows. Researchers will measure dural pulsation on MRI and compare it to patients' repor…

This study compares standard 2D X-ray guidance with a 3D imaging technique called OCT during leg artery procedures. About 166 adults with blocked leg arteries will be randomly assigned to one of two groups. The goal is to see if OCT helps doctors place balloons and stents more ac…