CHRONIC MYELOGENOUS LEUKEMIA
Clinical trials for CHRONIC MYELOGENOUS LEUKEMIA explained in plain language.
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Half-Matched donor transplant offers hope for blood cancer patients
Disease control CompletedThis study tested a less intense stem cell transplant for people with various blood cancers who are older or have other health issues. It used a half-matched family donor (like a parent or sibling) and a milder chemo and radiation preparation. The goal was to see how many patient…
Matched conditions: CHRONIC MYELOGENOUS LEUKEMIA
Phase: PHASE2 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated May 26, 2026 05:51 UTC
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Can a cheaper drug keep leukemia in check after stronger treatment?
Disease control CompletedThis study looked at whether people with chronic myeloid leukemia (CML) who achieved a good response after 12 months on nilotinib could switch to imatinib and keep that response. 13 newly diagnosed adults took part. The goal was to see if imatinib could maintain the remission at …
Matched conditions: CHRONIC MYELOGENOUS LEUKEMIA
Phase: NA • Sponsor: American University of Beirut Medical Center • Aim: Disease control
Last updated May 26, 2026 05:44 UTC
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New hope for leukemia patients: asciminib shows promise in phase 3 trial
Disease control CompletedThis study tested a daily pill called asciminib in 199 adults with chronic myeloid leukemia (CML) whose cancer had not responded well to at least two prior treatments. The goal was to see how many patients achieved a major molecular response (a key sign of disease control) after …
Matched conditions: CHRONIC MYELOGENOUS LEUKEMIA
Phase: PHASE3 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated May 26, 2026 05:43 UTC
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New drug combo may make bone marrow transplants safer for blood cancer patients
Disease control CompletedThis study looked at a new way to do bone marrow transplants for people with blood cancers like leukemia and lymphoma who don't have a perfectly matched donor. Instead of using a standard drug after transplant, doctors tested a different drug called bendamustine to see if it coul…
Matched conditions: CHRONIC MYELOGENOUS LEUKEMIA
Phase: PHASE1 • Sponsor: University of Arizona • Aim: Disease control
Last updated May 26, 2026 05:42 UTC
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New combo therapy shows promise for Hard-to-Treat CML
Disease control CompletedThis study looked at adding a new drug, asciminib, to the standard treatment imatinib for people with chronic myeloid leukemia (CML) who hadn't reached very low levels of cancer cells. 104 adults who had been on imatinib for at least a year were randomly assigned to add asciminib…
Matched conditions: CHRONIC MYELOGENOUS LEUKEMIA
Phase: PHASE2 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated May 26, 2026 04:37 UTC
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Leukemia drug holiday: many patients stay in remission after stopping nilotinib
Disease control CompletedThis study looked at whether people with chronic myeloid leukemia (CML) who had a deep response to the drug nilotinib could safely stop taking it without the cancer coming back. 215 adults who had been on nilotinib for at least two years were enrolled. The main finding was that m…
Matched conditions: CHRONIC MYELOGENOUS LEUKEMIA
Phase: PHASE2 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated May 07, 2026 18:38 UTC