CHRONIC MYELOGENOUS LEUKEMIA
Clinical trials for CHRONIC MYELOGENOUS LEUKEMIA explained in plain language.
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Cheaper drug tested to maintain leukemia control after stronger treatment
Disease control CompletedThis study tested whether patients with chronic myeloid leukemia could switch from an expensive, powerful drug (nilotinib) to a cheaper, more convenient drug (imatinib) and still keep their cancer under control. Researchers enrolled 13 newly diagnosed adults. The goal was to see …
Matched conditions: CHRONIC MYELOGENOUS LEUKEMIA
Phase: NA • Sponsor: American University of Beirut Medical Center • Aim: Disease control
Last updated Apr 03, 2026 14:43 UTC
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Leukemia patients test life without daily pills
Disease control CompletedThis study investigated whether patients with chronic myeloid leukemia (CML) who achieved a deep and sustained response to the drug nilotinib could safely stop taking it without their cancer returning. It enrolled 215 adults who had been on nilotinib for at least two years and ha…
Matched conditions: CHRONIC MYELOGENOUS LEUKEMIA
Phase: PHASE2 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Apr 03, 2026 14:42 UTC
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New drug combo tested to push leukemia into deeper remission
Disease control CompletedThis study tested whether adding a new drug called asciminib to the standard treatment imatinib could help patients with chronic myeloid leukemia (CML) achieve a deeper level of disease control. It involved 104 adults with CML who had been on imatinib for at least a year but hadn…
Matched conditions: CHRONIC MYELOGENOUS LEUKEMIA
Phase: PHASE2 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Apr 03, 2026 14:42 UTC
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New hope for CML patients who run out of options
Disease control CompletedThis study tested a pill called asciminib for adults with chronic-phase chronic myeloid leukemia (CML) who had already tried at least two other standard treatments and either didn't respond well or couldn't tolerate them. The main goal was to find the best daily dose and schedule…
Matched conditions: CHRONIC MYELOGENOUS LEUKEMIA
Phase: PHASE3 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Mar 23, 2026 15:14 UTC
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Scientists test new drug combo to make risky cancer transplants safer
Disease control CompletedThis study tested the safety of swapping out one drug (cyclophosphamide) for another (bendamustine) in the days following a bone marrow transplant. It involved 50 patients with various blood cancers who needed a transplant but lacked a perfectly matched donor. The goal was to see…
Matched conditions: CHRONIC MYELOGENOUS LEUKEMIA
Phase: PHASE1 • Sponsor: University of Arizona • Aim: Disease control
Last updated Mar 23, 2026 15:14 UTC
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New hope for blood cancer patients: gentler transplants from family donors
Disease control CompletedThis study tested a less intense bone marrow transplant procedure for adults with various blood cancers who needed a transplant but did not have a fully matched donor. It used stem cells from a half-matched family member (like a parent, child, or sibling) after a milder pre-trans…
Matched conditions: CHRONIC MYELOGENOUS LEUKEMIA
Phase: PHASE2 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated Mar 20, 2026 14:48 UTC