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Cord blood boost: new technique shows promise for tough leukemia cases

NCT ID NCT04103879

First seen Apr 02, 2026 · Last updated Jun 17, 2026 · Updated 14 times

Summary

This study tested a new way to prepare cord blood for transplant in 30 people with high-risk leukemia or myelodysplasia. The cord blood was treated with a molecule called UM171 to help it grow more stem cells. The goal was to see if this approach is safe and helps patients recover faster with fewer complications. Early results suggest it may improve survival and reduce side effects like graft-versus-host disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Erasmus Medical Center

    Rotterdam, Gelderland, 3015, Netherlands

  • Fred Hutchinson / University of Washington Cancer Consortium

    Seattle, Washington, 98109, United States

  • University of Colorado School of Medicine. Anschutz Medical Campus

    Aurora, Colorado, 80045, United States

Conditions

The condition(s) this trial relates to.

acute lymphoblastic leukemia acute myeloid leukemia blast phase chronic myelogenous leukemia, BCR-ABL1 positive myelodysplastic syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.