Chronic granulomatous disease (CGD)
Clinical trials for Chronic granulomatous disease (CGD) explained in plain language.
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Gene therapy aims to cure inherited immune disorder
Cure Recruiting nowChronic granulomatous disease (CGD) caused by p47phox deficiency is a rare, life-threatening genetic disorder that leaves people vulnerable to severe infections. Standard treatments include daily antibiotics and antifungal drugs, but they do not fix the underlying genetic defect.…
Matched conditions: CHRONIC GRANULOMATOUS DISEASE (CGD)
Phase 1/2 • Sponsor: Somagenetix AG • Aim: Cure
Last updated Sep 19, 2026 00:00 UTC
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Gene-Editing breakthrough aims to fix immune cells in rare disease
Disease control Recruiting nowThis early-stage trial tests a new gene-editing approach for X-linked chronic granulomatous disease (X-CGD), a rare immune disorder. Researchers will collect stem cells from 10 adult male participants, use base editing to correct the genetic mutation, and return the cells after m…
Matched conditions: CHRONIC GRANULOMATOUS DISEASE (CGD)
Phase 1/2 • Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Disease control
Last updated Aug 15, 2026 00:00 UTC
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Scientists launch major study to track rare immune diseases
Knowledge-focused Recruiting nowThis study is observing up to 3,500 people with immune system problems, including rare genetic conditions like chronic granulomatous disease and severe combined immunodeficiency. Researchers will track how these diseases change over time through blood tests, imaging, and checkups…
Matched conditions: CHRONIC GRANULOMATOUS DISEASE (CGD)
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Knowledge-focused
Last updated Sep 03, 2026 00:00 UTC
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New study probes immune system in rare disease patients
Knowledge-focused Recruiting nowThis study looks at how common certain antibodies and inflammatory markers are in people with chronic granulomatous disease (CGD). Researchers will measure levels of adenovirus-fighting antibodies and inflammatory cytokines in blood samples from 60 adults and children with CGD. T…
Matched conditions: CHRONIC GRANULOMATOUS DISEASE (CGD)
Sponsor: Ensoma • Aim: Knowledge-focused
Last updated Aug 19, 2026 00:00 UTC