CHILDREN, ONLY

This study is testing whether a specially designed digital game can help children aged 8 to 13 with type 1 diabetes improve their blood sugar control, confidence in managing their condition, and overall quality of life. The game is based on a health model and aims to make learnin…

This study compares two treatments for children with Crohn's disease: a single drug (infliximab or an immunosuppressant) versus a combination of both. The goal is to see which approach better controls the disease and leads to remission. About 128 children aged 6 to 18 with active…

This study looks at two ways to clean the blood in children with sepsis, a life-threatening infection. It compares continuous blood purification (done without stopping) to non-continuous methods. The goal is to see which approach helps more children survive 28 days after leaving …

This study looks at how different types of exercise affect heart and lung fitness in healthy school children aged 6 to 12. Researchers will compare aerobic exercises with low-intensity interval training to see which works better. The goal is to find simple ways to help kids stay …

This study looks at whether mat Pilates, when added to regular physical therapy, can reduce pain and improve posture in school-aged children with Upper Crossed Syndrome—a condition causing forward head, rounded shoulders, and a curved upper back. About 28 children aged 8 to 16 wi…

This study tests whether a virtual reality simulation that mimics an MRI scan can help children aged 4-18 stay calm enough to complete the real scan without anesthesia. About 288 children will either use the VR prep, read a booklet, or receive usual care before their MRI. The mai…

This study looks at whether inhaling isopropyl alcohol (rubbing alcohol) can reduce nausea and vomiting in children visiting the emergency room. About 84 kids aged 7 and older will be randomly assigned to get either the alcohol vapor, standard anti-nausea medicine (ondansetron), …

This large observational study is monitoring over 25,000 children to see how pneumococcal vaccines have changed the types of pneumococcus bacteria living in their noses. Researchers will compare children with ear infections to healthy children, looking at which bacterial strains …

This study looks at how different toilet sitting styles (squatting vs. sitting) affect ankle flexibility, constipation, and leg strength in school children aged 6-12. Researchers will measure ankle motion, leg power, and constipation symptoms in 191 kids who use either squat or s…

This study tests whether it's possible to track sleep and body rhythms in 30 children aged 3 to 6 in the pediatric ICU. Researchers will use a watch-like device and saliva tests, and try giving daytime light and limiting food to daytime hours. The goal is to see if these methods …

This study will observe up to 10,000 children and newborns with bacterial meningitis across France. Researchers aim to track which bacteria cause the infection, how often treatments fail, and how well vaccines are working. The goal is to improve future treatment and prevention st…

This study watches how often young children get ear infections from RSV, a common respiratory virus. Researchers will track 1,900 kids under 2 years old who visit the doctor for ear infections, with or without bronchiolitis. The goal is to understand how big a problem RSV-related…

This study follows 300 critically ill children who had sepsis for five years after they leave the hospital. Researchers want to see how sepsis affects their growth, brain development, survival, and quality of life. The goal is to better understand the long-term challenges these c…