Central nervous system neoplasms
Clinical trials for Central nervous system neoplasms explained in plain language.
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New hope for breast cancer patients with brain tumors: drug combo trial underway
Disease control Recruiting nowThis study tests a combination of two drugs, elacestrant and abemaciclib, in people with a specific type of breast cancer (ER-positive, HER2-negative) that has spread to the brain. The goal is to see if the combination can shrink or control brain tumors. The trial involves about …
Matched conditions: CENTRAL NERVOUS SYSTEM NEOPLASMS
Phase 1/2 • Sponsor: Stemline Therapeutics, Inc. • Aim: Disease control
Last updated Sep 11, 2026 00:00 UTC
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Immune cells engineered to fight brain cancer in kids
Disease control Recruiting nowThis early-phase study tests the safety of a new cell therapy called B7-H3 CAR T cells for children and young adults whose brain tumors have come back or are growing despite standard treatment. The therapy uses the patient's own immune cells, modified to target a protein (B7-H3) …
Matched conditions: CENTRAL NERVOUS SYSTEM NEOPLASMS
Phase 1 • Sponsor: Robbie Majzner • Aim: Disease control
Last updated Sep 05, 2026 00:00 UTC
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New pill shows promise in early brain tumor trial
Disease control Recruiting nowThis early-stage study tests an oral drug called ONC206 in adults with brain tumors that have come back. The main goal is to find the safest dose and check for side effects. About 102 participants will take the drug once or several times a week.
Matched conditions: CENTRAL NERVOUS SYSTEM NEOPLASMS
Phase 1 • Sponsor: Jazz Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC