CENTRAL NERVOUS SYSTEM NEOPLASMS
Clinical trials for CENTRAL NERVOUS SYSTEM NEOPLASMS explained in plain language.
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New pill takes on brain tumors: first human trial begins
Disease control Recruiting nowThis early-phase study tests an oral drug called ONC206 in 102 adults with brain tumors that have come back or are rare. The main goal is to find the safest dose and understand side effects. Participants take the drug by mouth on a weekly schedule, and researchers monitor for any…
Matched conditions: CENTRAL NERVOUS SYSTEM NEOPLASMS
Phase: PHASE1 • Sponsor: Jazz Pharmaceuticals • Aim: Disease control
Last updated May 26, 2026 04:33 UTC
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Immune cells delivered directly to the brain show promise for kids with cancer
Disease control Recruiting nowThis early-stage study tests a new treatment for children and young adults (up to age 21) with certain brain tumors that have come back or not responded to standard therapy. The treatment uses the patient's own immune cells, modified to target a protein called B7-H3 on tumor cell…
Matched conditions: CENTRAL NERVOUS SYSTEM NEOPLASMS
Phase: PHASE1 • Sponsor: St. Jude Children's Research Hospital • Aim: Disease control
Last updated May 26, 2026 04:26 UTC
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Promising combo targets breast cancer brain metastases in early trial
Disease control Recruiting nowThis study tests a combination of two drugs, elacestrant and abemaciclib, in people with a specific type of breast cancer (ER-positive, HER2-negative) that has spread to the brain. The goal is to see if the combination can shrink or control brain tumors. About 73 adults are being…
Matched conditions: CENTRAL NERVOUS SYSTEM NEOPLASMS
Phase: PHASE1, PHASE2 • Sponsor: Stemline Therapeutics, Inc. • Aim: Disease control
Last updated May 20, 2026 11:57 UTC