CD40L-hyperigm syndrome

Clinical trials for CD40L-hyperigm syndrome explained in plain language.

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Gene editing tackles rare immune disease in first human test

Disease control Recruiting now

This study tests a one-time gene therapy for a single person with X-linked Hyper-IgM syndrome, a rare immune disorder caused by a faulty CD40L gene. The participant's own stem cells and T cells are collected, edited in a lab to fix the gene mutation, and then infused back after c…

Matched conditions: CD40L-HYPERIGM SYNDROME

Phase 1/2 • Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Disease control

Last updated Aug 02, 2026 00:00 UTC

CD40L-hyperigm syndrome

Get alerted when new CD40L-hyperigm syndrome trials appear

Gene editing tackles rare immune disease in first human test