CARDIAC SARCOIDOSIS

This study compares two treatments for cardiac sarcoidosis, a condition where inflammation damages the heart. About 194 adults with active heart sarcoidosis will get either a low-dose prednisone/methotrexate combo or standard-dose prednisone alone. The goal is to see if the combo…

This study explores whether a radioactive tracer called Tc 99m tilmanocept, already used for other conditions, can help identify cardiac sarcoidosis—a disease where immune cells form clumps in the heart. Researchers will compare this new imaging method to standard PET and MRI sca…

This study tests whether taking a drug called sotagliflozin along with a ketogenic diet can make heart inflammation easier to see on a PET scan. Researchers will enroll 40 healthy volunteers to find the best way to suppress normal heart sugar uptake, which can hide inflammation. …

This study tests whether a special PET/CT scan using a tracer called PentixaFor can accurately detect inflammation in the heart muscle. It focuses on three conditions: rejection after heart transplant, cardiac sarcoidosis, and drug-related myocarditis. About 69 adults will be sca…

This study is looking for new genes and blood markers that can help predict who will get arrhythmogenic cardiomyopathy (AVC), a genetic heart condition that can cause sudden cardiac arrest. Researchers will enroll 1000 people, including patients with AVC or unexplained cardiac ar…

This study aims to improve how doctors diagnose and predict the course of rare heart muscle diseases (cardiomyopathies) using advanced MRI scans. Researchers will enroll 1000 people with suspected rare cardiomyopathies to test new imaging methods. The goal is to provide clearer, …