CARDIAC FAILURE

This study tests whether social prescribing—connecting patients with community resources for issues like housing, transportation, or loneliness—can help women with heart failure stick to their medications and improve their quality of life. About 200 women at high social risk will…

This study tests whether adding landiolol, a short-acting heart medication, to the fluid used to preserve the heart during mitral valve surgery can prevent a dangerous condition called low cardiac output syndrome. About 1500 adults having elective mitral valve repair or replaceme…

This study looks at tiny molecules called microRNAs in the blood of 250 adult heart transplant patients. The goal is to see if these molecules can help predict who will develop infections or organ rejection. By better understanding each patient's immune state, doctors hope to per…

This study follows 100 adults who needed a machine called ECMO to support their heart and lungs after a severe failure. Researchers want to understand how muscle wasting and weakness affect patients' recovery and quality of life. The goal is to find better ways to help people reg…

This study looks at how different types of blood platelets change in adults who need ECMO support for severe heart or lung failure. Researchers will take blood samples on days 1, 3, and 7 after ECMO starts to measure shifts in platelet populations. The goal is to better understan…

This study looks at how the heart's structure and function change one year after a minimally invasive procedure to fix the aorta. Researchers will use heart MRI scans to measure changes in heart muscle mass and pumping ability. The study involves 40 adults with aortic aneurysms o…

This study is looking at tiny molecules called microRNAs in the blood of 150 children who have had a heart transplant. The goal is to see if these molecules can help predict which children will get an infection or have their body reject the new heart. Researchers hope this will l…