Cancer pain

Researchers at Dana-Farber Cancer Institute are testing Healing Gardens, a mobile game that delivers pain-focused cognitive behavioral therapy and cancer pain education. The study enrolls 46 adults with advanced solid tumors who have chronic pain related to cancer or its treatmen…

This trial investigates whether adding the non-opioid drugs metamizole (dipyrone) or ibuprofen to standard opioid therapy provides better pain relief for people with cancer-related pain. About 318 adults with advanced cancer and moderate to severe pain will receive either metamiz…

This trial is testing whether a single, higher dose of radiation (8 Gy) can relieve pain from bone metastases as effectively as a standard course of five smaller doses (20 Gy total). The study includes adults with cancer that has spread to the bones and who have significant pain.…

This study tests whether virtual reality (VR) guided imagery can reduce pain in people with stage III or IV breast cancer. Ninety participants will be split into three groups: one using immersive VR (headset), one using non-immersive VR (computer screen), and a control group rece…

This study tests whether adding a new drug (3D1002) to a standard painkiller (oxycodone) can better control moderate to severe cancer pain. About 177 adults with cancer and ongoing pain will receive either the combination or standard treatment. The goal is to see if the new appro…

This study looks at whether hydromorphone sustained-release tablets can safely relieve moderate to severe cancer pain in elderly patients who also have kidney issues. Researchers will compare these patients to those with normal kidney function, monitoring pain relief, kidney func…

This study tests whether doctors can safely perform ultrasound-guided pain procedures, like nerve blocks, at home for patients with chronic or cancer pain. It includes 100 adults already receiving home hospital care. The goal is to see if this approach reduces pain, cuts down on …

This study will compare two ways of teaching nursing students about cancer pain management: traditional classroom lectures and an e-learning course with AI-powered avatar lectures and gamified scenarios. About 100 nursing students will take part, and researchers will measure thei…

This study watches 15 adults with severe cancer pain who are getting a procedure called cordotomy to block pain signals. Researchers will use MRI scans to check for swelling in the spinal cord right after and one month later. The goal is to see if swelling relates to how well the…