Burn

This study looks at whether a specific type of breathing support (adaptive support ventilation) combined with carefully controlled fluid replacement can help adults with severe burns who need a breathing machine. The goal is to see if this approach improves oxygen levels, lung fu…

This study compares two ways of using breathing machines in adults with severe burns (covering 20% or more of the body). One method, called Adaptive Support Ventilation (ASV), automatically adjusts the machine's settings to the patient's needs. The other is standard lung-protecti…

This early study is testing a new dressing made from sodium hyaluronate and carbomer hydrogel for first and shallow second-degree burns. The goal is to see if it helps the burn heal completely within 50 days and reduces itching. The study will involve 30 adults with burn wounds o…

Many burn survivors live with persistent pain that disrupts daily life, and negative thoughts about pain can make it worse. Researchers are testing an 8-week cognitive behavioral therapy program delivered by video to see if it reduces pain interference and pain catastrophizing mo…

Researchers are testing custom silicone splints that fit inside the mouth to gently stretch facial tissue that has tightened or scarred after burns, trauma, or gunshot wounds. The study includes people aged 7 and older whose scars limit mouth opening, chewing, speaking, or facial…

This trial tests whether brief, video-guided jaw relaxation or breathing exercises can reduce anxiety and fear in children aged 4 to 10 who are having burn dressings changed. Children in a pediatric burn unit will be randomly assigned to one of three groups: jaw relaxation, breat…

This study tests whether adding a medication called 5-fluorouracil to a standard steroid treatment helps improve thick, raised burn scars more than the steroid alone. Both treatments are delivered through tiny holes made by a CO2 laser, which helps the medications reach deeper in…

This study tests whether a guided laughter exercise, called Laughie, can help people with second-degree burns feel less pain and anxiety during dressing changes. 88 adults will either watch and mimic a video of their own laughter before the procedure or receive standard care. The…