BREAST NEOPLASM
Clinical trials for BREAST NEOPLASM explained in plain language.
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Hope for advanced breast cancer: new combo targets resistant tumors
Disease control OngoingThis phase 3 study tests whether adding abemaciclib to fulvestrant can slow or stop the growth of a common type of advanced breast cancer (HR+, HER2-) that has worsened despite prior treatment with CDK4/6 inhibitors and hormone therapy. About 368 participants will receive either …
Matched conditions: BREAST NEOPLASM
Phase: PHASE3 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated May 26, 2026 03:55 UTC
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New hope for advanced breast cancer: drug combo shows promise in phase 2 trial
Disease control OngoingThis study tests a drug called trifluridine/tipiracil in 52 women with advanced ER-positive, HER2-negative breast cancer that has progressed after prior chemotherapy. The goal is to see if the drug can slow cancer growth and improve quality of life. Participants take the drug ora…
Matched conditions: BREAST NEOPLASM
Phase: PHASE2 • Sponsor: Borstkanker Onderzoek Groep • Aim: Disease control
Last updated May 22, 2026 13:53 UTC
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Heart-Sparing proton therapy tested in advanced breast cancer
Disease control OngoingThis study tests a precise type of radiation called proton therapy given after surgery for stage II/III breast cancer. The goal is to see if it can effectively treat cancer while reducing damage to the heart and other organs. About 220 women will receive this treatment and be fol…
Matched conditions: BREAST NEOPLASM
Phase: PHASE2 • Sponsor: Proton Collaborative Group • Aim: Disease control
Last updated May 15, 2026 11:56 UTC
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New imaging technique could reveal how breast cancer drugs work inside the body
Knowledge-focused OngoingThis study uses a special PET scan called FLT PET/CT to look at how active breast cancer tumors are before and during treatment with two drugs (ribociclib and paclitaxel). About 20 adults with metastatic breast cancer that has spread beyond the liver and bones will take part. The…
Matched conditions: BREAST NEOPLASM
Phase: PHASE1 • Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated May 26, 2026 03:56 UTC
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Can a website help cancer patients protect their future family?
Knowledge-focused OngoingThis study looks at whether a special website can help women with cancer make better decisions about preserving their ability to have children after treatment. About 130 women with breast, colorectal, or reproductive cancers, or lymphoma, will use the website or receive usual car…
Matched conditions: BREAST NEOPLASM
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated May 26, 2026 03:56 UTC
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New study tracks nerve pain in breast cancer drug T-DM1
Knowledge-focused OngoingThis study follows 36 people with HER2-positive breast cancer who are receiving the drug T-DM1. Researchers want to learn how often and how severely nerve damage (peripheral neuropathy) occurs during treatment. Participants will report their symptoms through questionnaires, helpi…
Matched conditions: BREAST NEOPLASM
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated May 26, 2026 03:55 UTC
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New imaging method peers inside breast tumors without surgery
Knowledge-focused OngoingThis study tests a new imaging method using a radioactive tracer called [18F]ISO-1 to measure sigma-2 receptors in breast cancer. These receptors are linked to how fast cancer cells multiply. About 30 adults with known or suspected breast cancer will receive a PET/CT scan to see …
Matched conditions: BREAST NEOPLASM
Phase: PHASE1 • Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated May 22, 2026 13:53 UTC