BREAST CANCER METASTATIC
Clinical trials for BREAST CANCER METASTATIC explained in plain language.
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New combo therapy tested for hard-to-treat breast cancer
Disease control OngoingThis early-stage trial tests the safety of combining two drugs, olaparib and vorinostat, in people with advanced breast cancer that has returned or spread. The study includes 28 adults whose cancer is not HER2-positive. The goal is to find the best dose and check for side effects…
Matched conditions: BREAST CANCER METASTATIC
Phase: PHASE1 • Sponsor: The Methodist Hospital Research Institute • Aim: Disease control
Last updated May 26, 2026 03:15 UTC
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Blood test finds hidden cancer; new drug aims to stop it
Disease control ENROLLING_BY_INVITATIONThis study is for people with a certain type of advanced breast cancer (HR+, HER2-low). First, a blood test looks for leftover cancer DNA after one month of standard hormone therapy and a CDK4/6 inhibitor. Those with positive results then receive trastuzumab deruxtecan, a targete…
Matched conditions: BREAST CANCER METASTATIC
Phase: PHASE2 • Sponsor: UNICANCER • Aim: Disease control
Last updated May 22, 2026 14:03 UTC
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Engineered immune cells take on Hard-to-Treat breast cancer
Disease control OngoingThis early-stage study tests a new two-part treatment for people with advanced breast cancer that has stopped responding to standard therapies. Participants receive a single infusion of their own engineered immune cells (CLBR001) followed by cycles of an antibody drug (ABBV-461).…
Matched conditions: BREAST CANCER METASTATIC
Phase: PHASE1 • Sponsor: Calibr, a division of Scripps Research • Aim: Disease control
Last updated May 20, 2026 11:53 UTC
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New drug combo shows promise for Hard-to-Treat breast cancer
Disease control OngoingThis study tests a combination of two drugs, sacituzumab govitecan and trastuzumab, in 28 people with HER2+ breast cancer that has spread and has been previously treated. The goal is to see if this combination can shrink tumors or slow cancer growth. Participants receive both dru…
Matched conditions: BREAST CANCER METASTATIC
Phase: PHASE2 • Sponsor: Adrienne G. Waks • Aim: Disease control
Last updated May 13, 2026 16:01 UTC
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Blood test could predict when breast cancer patients can safely stop treatment
Knowledge-focused OngoingThis study looks at using a personalized blood test (ctDNA) to detect tiny amounts of cancer DNA in 50 patients with HER2-positive metastatic breast cancer who have had a good response to anti-HER2 therapy for at least two years. The goal is to see if the test can help doctors de…
Matched conditions: BREAST CANCER METASTATIC
Sponsor: Nagoya City University • Aim: Knowledge-focused
Last updated May 26, 2026 03:21 UTC
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Blood tests may spare breast cancer patients from unnecessary scans
Knowledge-focused OngoingThis study looks at whether simple blood tests can tell when a scan is needed for women with metastatic breast cancer. About 97 women on standard hormone therapy will give blood samples at regular checkups. The goal is to create a smart rule that safely skips some scans, saving t…
Matched conditions: BREAST CANCER METASTATIC
Sponsor: The Christie NHS Foundation Trust • Aim: Knowledge-focused
Last updated May 26, 2026 03:19 UTC
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Researchers to watch how breast cancer drugs work in everyday care
Knowledge-focused TerminatedThis study aimed to collect information from routine medical care for people with a certain type of advanced breast cancer (HR+/HER2-). Researchers planned to track side effects and how well treatments worked, without giving any new drugs. The study was withdrawn before enrolling…
Matched conditions: BREAST CANCER METASTATIC
Sponsor: SciClone Pharmaceuticals • Aim: Knowledge-focused
Last updated May 26, 2026 03:04 UTC