BREAST CANCER, METASTATIC
Clinical trials for BREAST CANCER, METASTATIC explained in plain language.
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New drug combo aims to stop advanced breast Cancer's repair system
Disease control OngoingThis early-stage trial is testing whether two existing drugs, olaparib and vorinostat, can be safely used together to treat advanced breast cancer that has returned or spread. The study aims to find the safest dose and see if blocking two of the cancer's repair mechanisms helps c…
Matched conditions: BREAST CANCER, METASTATIC
Phase: PHASE1 • Sponsor: The Methodist Hospital Research Institute • Aim: Disease control
Last updated Apr 03, 2026 14:42 UTC
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Blood test trial aims to outsmart breast cancer relapse
Disease control ENROLLING_BY_INVITATIONThis study has two parts. First, it uses a blood test to find patients with a specific type of metastatic breast cancer who still have cancer DNA in their blood after one month of standard therapy. In the second part, those patients switch to a different drug, trastuzumab deruxte…
Matched conditions: BREAST CANCER, METASTATIC
Phase: PHASE2 • Sponsor: UNICANCER • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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New hope for metastatic breast cancer patients who've run out of options
Disease control OngoingThis study is testing whether combining two targeted drugs—sacituzumab govitecan and trastuzumab—can help control metastatic HER2-positive breast cancer that has progressed after standard treatments. The trial will enroll about 28 patients who have already received specific prior…
Matched conditions: BREAST CANCER, METASTATIC
Phase: PHASE2 • Sponsor: Adrienne G. Waks • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC
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Blood test could guide when to stop breast cancer treatment
Knowledge-focused OngoingThis study is testing a personalized blood test to see if it can detect tiny traces of cancer in patients with advanced HER2-positive breast cancer who have responded very well to treatment for over two years. The goal is to gather knowledge that might help doctors decide if and …
Matched conditions: BREAST CANCER, METASTATIC
Sponsor: Nagoya City University • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:40 UTC
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Study withdrawn before launch: what we could have learned about breast cancer treatments
Knowledge-focused TerminatedThis study aimed to collect real-world information about how well treatments work and what side effects people experience when managing advanced breast cancer. Researchers planned to follow adults with hormone-positive, HER2-negative advanced breast cancer during their routine me…
Matched conditions: BREAST CANCER, METASTATIC
Sponsor: SciClone Pharmaceuticals • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:17 UTC
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Blood tests could replace frequent scans for some breast cancer patients
Knowledge-focused OngoingThis study aims to develop a blood test system to monitor advanced breast cancer, potentially reducing the need for frequent CT/MRI scans. It involves 97 patients with ER-positive/HER2-negative metastatic breast cancer who are starting first-line hormone therapy. Researchers will…
Matched conditions: BREAST CANCER, METASTATIC
Sponsor: The Christie NHS Foundation Trust • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:14 UTC