BRAIN TUMOR ADULT

This early-phase trial tests a new cell therapy called B7-H3 CAR T cells for children and young adults whose brain tumors have come back or are growing despite standard treatment. The therapy uses a patient's own immune cells, modified to recognize and attack a protein (B7-H3) fo…

This study tests a stepped-care program to support relatives of people with serious brain diseases or injuries. 160 relatives will either receive the program or usual care. The goal is to reduce caregiver burden and improve well-being.

This study looks at whether a 3-month supervised exercise program is possible for adults with brain tumors. Researchers will track how many patients join and stick with the program, and measure changes in quality of life, anxiety, depression, and cancer symptoms. The goal is to s…

This study tests whether special MRI scans can spot areas of brain tumor that standard scans miss. About 20 adults with suspected high-grade glioma will get extra scans before surgery. The goal is to better understand how far the tumor has spread, which could help doctors plan mo…

This study tests whether a Mixed Reality Viewer helps surgeons plan brain tumor removal more accurately and quickly than current methods. About 54 adults needing brain surgery will participate. Researchers will compare incision planning and timing between the new viewer and stand…

This study tests a new AI tool that helps surgeons see brain tumors more clearly during surgery using ultrasound. The tool is designed to make it easier to tell tumor tissue from healthy brain, which could lead to safer and more complete tumor removal. About 100 adults scheduled …

This study tests whether a short course of physical therapy, with or without brain stimulation, before surgery can help the brain reorganize motor function in adults with high-grade glioma near the movement area. About 63 participants will be randomly assigned to standard care, p…

This study looks at whether a computer can figure out what a person is saying by reading their brain signals during awake brain tumor surgery. Twenty adults with brain tumors near language areas will have special electrodes placed on their brain while they name pictures. The goal…

This study looks at how standard brain radiation therapy affects thinking and memory in 40 adults with brain tumors (primary or metastatic). Researchers will measure specific proteins in the blood and use brain scans to understand the biological changes behind cognitive decline. …