BRAIN DISEASE

This study looks at people who already have a deep brain stimulation (DBS) device for movement problems like tremor or stroke. Researchers will adjust the device's settings and then test how well participants can move their hands, speak, swallow, and make facial expressions. The …

This study aims to learn more about stroke and TIA by observing up to 4,000 adults who have had or are at risk for these conditions. Researchers will collect data from standard medical tests and some extra research procedures, such as blood draws and brain scans, to track changes…

This study follows 150 people with early-stage Parkinson's disease to see how symptoms like walking problems and thinking changes differ between two types: one that starts in the brain and one that starts in the body. Participants will have yearly check-ups, brain scans, and test…

This study looks at how things like education, race, and income might affect a person's memory and thinking after a stroke. Researchers will talk with 450 adults who had a stroke and review their brain scans. The goal is to understand why some people recover better than others.

This study tests whether temporarily stimulating a specific part of the brain can improve hand, arm, and speech abilities in people who had a stroke at least 6 months ago. Ten participants will have a thin wire placed in the brain for less than 30 days to deliver mild electrical …

This study aims to understand how infections and inflammation harm the brain and nerves by observing people with these conditions. Participants, aged 2 and older, will provide blood, urine, saliva, and may have MRI scans and spinal taps. No new treatments are tested; the goal is …

This study follows 213 adults recovering from a first ischemic stroke to see if the intensity of rehabilitation (3-5 sessions per day vs. 1 session per day) affects their functional recovery at six months. It also compares outcomes between patients whose stroke was linked to atri…