BRAF V600E
Clinical trials for BRAF V600E explained in plain language.
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New pill targets hard-to-treat cancers with KRAS and BRAF mutations
Disease control Recruiting nowThis early-stage study tests an oral drug called S241656 in adults with advanced cancers that have certain gene changes (KRAS, BRAF, or related mutations). The drug is given alone or with other cancer treatments. The goal is to find safe doses and see if the drug shrinks tumors. …
Matched conditions: BRAF V600E
Phase: PHASE1, PHASE2 • Sponsor: Institut de Recherches Internationales Servier • Aim: Disease control
Last updated May 26, 2026 08:32 UTC
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New 4-Drug cocktail takes on deadly colorectal cancer
Disease control Recruiting nowThis study tests a combination of four drugs (sintilimab, ipilimumab, cetuximab, and dabrafenib) in people with a specific, hard-to-treat type of colorectal cancer that has spread. The cancer must have a BRAF V600E mutation and be microsatellite stable (MSS). The goal is to see i…
Matched conditions: BRAF V600E
Phase: PHASE2 • Sponsor: Tianjin Medical University Cancer Institute and Hospital • Aim: Disease control
Last updated May 19, 2026 12:01 UTC
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Scientists rebiopsy lung tumors to catch resistance early
Knowledge-focused Recruiting nowThis study looks at why some lung cancers stop responding to targeted therapy. Researchers will take small tumor samples before and after treatment to find early signs of resistance. The goal is to develop better drug combinations that can overcome resistance. About 100 adults wi…
Matched conditions: BRAF V600E
Sponsor: University of Colorado, Denver • Aim: Knowledge-focused
Last updated May 26, 2026 09:06 UTC