BRAF V600E
Clinical trials for BRAF V600E explained in plain language.
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Promising new cocktail takes on deadly colorectal cancer
Disease control Recruiting nowThis study tests a combination of four drugs (sintilimab, ipilimumab, cetuximab, and dabrafenib) in people with a specific type of advanced colorectal cancer that has a BRAF V600E mutation and is microsatellite stable. These cancers are hard to treat and don't respond well to sta…
Matched conditions: BRAF V600E
Phase: PHASE2 • Sponsor: Tianjin Medical University Cancer Institute and Hospital • Aim: Disease control
Last updated May 13, 2026 16:03 UTC
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New pill targets hard-to-treat cancers with KRAS and BRAF mutations
Disease control Recruiting nowThis early-phase study tests an oral drug called S241656 in adults with advanced cancers that have certain gene changes (KRAS, BRAF, and others). The drug is given alone or with other cancer treatments. The goal is to find safe doses and see if the drug shrinks tumors. About 554 …
Matched conditions: BRAF V600E
Phase: PHASE1, PHASE2 • Sponsor: Institut de Recherches Internationales Servier • Aim: Disease control
Last updated May 12, 2026 13:40 UTC
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Lung cancer rebiopsy study seeks to outsmart drug resistance
Knowledge-focused Recruiting nowThis study looks at why some lung cancer cells survive targeted treatment. Researchers will take small tissue samples (biopsies) before and two weeks after starting therapy to spot early signs of resistance. The goal is to find ways to block these survival pathways and make treat…
Matched conditions: BRAF V600E
Sponsor: University of Colorado, Denver • Aim: Knowledge-focused
Last updated May 14, 2026 12:05 UTC