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Birth asphyxia
Clinical trials for Birth asphyxia explained in plain language.
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Can a common drug protect Babies' brains after a difficult birth?
Disease control CompletedBirth asphyxia, when a baby does not get enough oxygen around birth, can lead to brain injury and long-term disability. This Phase 1 trial in Uganda tests sildenafil, a drug that widens blood vessels, in 18 newborns with birth asphyxia. Researchers want to find the highest dose t…
Matched conditions: BIRTH ASPHYXIA
Phase 1 • Sponsor: Pia Wintermark • Aim: Disease control
Last updated Sep 17, 2026 00:00 UTC
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Could a simple salt save newborn brains? trial tests magnesium for birth asphyxia
Disease control CompletedThis study tested whether giving magnesium sulfate to full-term or near-term newborns with moderate to severe birth asphyxia could reduce death and brain damage. 178 infants were randomly assigned to receive either standard care or magnesium sulfate. Researchers tracked survival,…
Matched conditions: BIRTH ASPHYXIA
Sponsor: University of Health Sciences Lahore • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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Can a liquid Erectile-Dysfunction drug help repair Newborns' brains after oxygen starvation?
Symptom relief CompletedWhen a baby is deprived of oxygen around birth, doctors cool the body to limit brain damage, but some infants still suffer lasting injury. This early-stage trial tests whether adding oral sildenafil, a drug that widens blood vessels, can further protect or repair the brain. Resea…
Matched conditions: BIRTH ASPHYXIA
Phase 1 • Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre • Aim: Symptom relief
Last updated Sep 17, 2026 00:00 UTC
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Gadget that coaches baby resuscitation could save lives
Knowledge-focused CompletedThis study tested a device called the Augmented Infant Resuscitator (AIR), which attaches to standard bag-mask ventilators used to help newborns breathe. It gives real-time visual feedback to clinicians on their ventilation technique. Researchers enrolled 250 birth attendants to …
Matched conditions: BIRTH ASPHYXIA
Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC