B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA (B-ALL)
Clinical trials for B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA (B-ALL) explained in plain language.
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New hope for tough leukemia: experimental drug AZD0486 enters human trials
Disease control Recruiting nowThis study tests an experimental drug called AZD0486 in adolescents and adults whose B-cell acute lymphoblastic leukemia (B-ALL) has returned or not responded to at least two prior treatments. The trial has three parts: first, finding a safe dose; second, optimizing that dose; an…
Matched conditions: B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA (B-ALL)
Phase: PHASE1, PHASE2 • Sponsor: AstraZeneca • Aim: Disease control
Last updated Jun 23, 2026 23:33 UTC
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New antibody drug takes aim at relapsed leukemia
Disease control Recruiting nowThis study tests a new drug called AZD4512 for people with B-cell acute lymphoblastic leukemia (B-ALL) that has returned or not responded to treatment. The drug is an antibody-drug conjugate that delivers a toxic payload directly to cancer cells. The trial has two parts: first, f…
Matched conditions: B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA (B-ALL)
Phase: PHASE1, PHASE2 • Sponsor: AstraZeneca • Aim: Disease control
Last updated Jun 23, 2026 23:32 UTC
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New CAR T-Cell therapy shows promise for kids with tough leukemia
Disease control Recruiting nowThis study is testing a new version of CAR T-cell therapy for children with B-cell acute lymphoblastic leukemia (B-ALL) that has come back or not responded to standard treatments. The therapy uses the patient's own immune cells, modified to target cancer cells. The trial aims to …
Matched conditions: B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA (B-ALL)
Phase: PHASE1, PHASE2 • Sponsor: Stephan Grupp MD PhD • Aim: Disease control
Last updated Jun 23, 2026 11:55 UTC
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New cell therapy JY231 targets tough leukemia in early human test
Disease control Recruiting nowThis early study is testing a new treatment called JY231 for people with B-cell acute lymphoblastic leukemia (B-ALL), a type of blood cancer. The main goal is to check if JY231 is safe and tolerable, and to see if it can help control the disease. About 20 adults and children up t…
Matched conditions: B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA (B-ALL)
Phase: EARLY_PHASE1 • Sponsor: 920th Hospital of Joint Logistics Support Force of People's Liberation Army of China • Aim: Disease control
Last updated Jun 15, 2026 19:08 UTC
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Experimental injection targets tough blood cancers and anemia
Disease control Recruiting nowThis early-phase study tests a new treatment called GT801 in 28 adults with certain blood cancers (like leukemia and lymphoma) or an autoimmune condition that destroys red blood cells. The goal is to see if the injection is safe and can shrink tumors or control the autoimmune dis…
Matched conditions: B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA (B-ALL)
Phase: EARLY_PHASE1 • Sponsor: Grit Biotechnology • Aim: Disease control
Last updated Jun 15, 2026 19:04 UTC
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CAR T-Cell survivors: what happens years later?
Knowledge-focused Recruiting nowThis study follows 80 children and young adults who received CAR T-cell therapy for B-cell acute lymphoblastic leukemia (B-ALL) at least two years ago. Researchers want to see how feasible it is to track their long-term health, including any new or lasting side effects, brain fun…
Matched conditions: B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA (B-ALL)
Sponsor: St. Jude Children's Research Hospital • Aim: Knowledge-focused
Last updated Jun 23, 2026 11:56 UTC
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Leukemia treatment may erase vaccine protection—study tests if re-vaccination works
Knowledge-focused Recruiting nowThis study looks at whether children and young adults (up to age 21) treated for B-cell acute lymphoblastic leukemia with the immunotherapy drug blinatumomab still have protection from routine childhood vaccines. Researchers will measure antibody levels for diseases like tetanus,…
Matched conditions: B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA (B-ALL)
Sponsor: Arkansas Children's Hospital Research Institute • Aim: Knowledge-focused
Last updated Jun 18, 2026 11:47 UTC