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Leukemia treatment may erase vaccine protection—study tests if re-vaccination works

NCT ID NCT07422337

First seen Feb 22, 2026 · Last updated Jun 17, 2026 · Updated 20 times

Summary

This study looks at whether children and young adults (up to age 21) treated for B-cell acute lymphoblastic leukemia with the immunotherapy drug blinatumomab still have protection from routine childhood vaccines. Researchers will measure antibody levels for diseases like tetanus, hepatitis B, and measles. If protection is low, they will see if re-vaccination can restore it. The goal is to create a clear vaccination plan for these patients.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-••••

Locations

  • Arkansas Children's

    RECRUITING

    Little Rock, Arkansas, 72202, United States

    Contact Phone: •••-•••-••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Arkansas Children's Northwest

    RECRUITING

    Springdale, Arkansas, 72762, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

The condition(s) this trial relates to.

B-cell acute lymphoblastic leukemia B-cell childhood acute lymphoblastic leukemia Burkitt lymphoma Leukemia, B-Cell lymphoblastic lymphoma lymphoma neoplasm precursor B-cell acute lymphoblastic leukemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.