B-ALL
Clinical trials for B-ALL explained in plain language.
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Engineered immune cells show promise against hard-to-treat childhood blood cancers
Disease control CompletedThis study tested a new treatment for children and young adults (ages 1-39) with B-cell leukemia or lymphoma that did not respond to standard therapy. Researchers took participants' white blood cells, modified them in a lab to target the CD22 protein on cancer cells, and infused …
Matched conditions: B-ALL
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 26, 2026 07:35 UTC
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Experimental CAR-T therapy shows promise for tough leukemia
Disease control CompletedThis early-stage study tested a new cell therapy called ThisCART19A in 10 adults with relapsed or refractory B-cell leukemia (a type of blood cancer that returned or didn't respond to standard treatment). The main goals were to check safety and find the right dose. Researchers tr…
Matched conditions: B-ALL
Phase: PHASE1 • Sponsor: Zhejiang University • Aim: Disease control
Last updated May 26, 2026 07:27 UTC
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New drug combo shows promise for Hard-to-Treat blood cancers
Disease control CompletedThis early-phase study tested a combination of two drugs, acalabrutinib and ACP-319, in 40 people with B-cell cancers such as non-Hodgkin lymphoma, multiple myeloma, and B-cell acute lymphoblastic leukemia. The goal was to see if the combination is safe and effective. Participant…
Matched conditions: B-ALL
Phase: PHASE1, PHASE2 • Sponsor: Acerta Pharma BV • Aim: Disease control
Last updated May 22, 2026 13:54 UTC
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Engineered immune cells take aim at Hard-to-Treat blood cancers
Disease control CompletedThis study tested whether a new type of immune cell therapy, called CD22 CAR T cells, could be made from the blood of adults with certain blood cancers (leukemia and lymphoma) that had come back or not responded to treatment. The main goals were to see if the cells could be succe…
Matched conditions: B-ALL
Phase: PHASE1 • Sponsor: Matthew Frank • Aim: Disease control
Last updated May 18, 2026 12:07 UTC