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New drug combo shows promise for Hard-to-Treat blood cancers

NCT ID NCT02328014

First seen Nov 01, 2025 · Last updated Jun 05, 2026 · Updated 31 times

Summary

This early-stage study tested a combination of two drugs, acalabrutinib and ACP-319, in 40 people with B-cell cancers such as non-Hodgkin lymphoma, multiple myeloma, and B-cell acute lymphoblastic leukemia. The goal was to check safety and how well the drugs work together. Participants had to have a confirmed diagnosis and be in relatively good health. The study is now complete.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Research Site

    Orange, California, 92868, United States

  • Research Site

    Bethesda, Maryland, 20892, United States

  • Research Site

    Rochester, New York, 14642, United States

  • Research Site

    Portland, Oregon, 97239, United States

  • Research Site

    Nashville, Tennessee, 37203, United States

  • Research Site

    Austin, Texas, 78705, United States

  • Research Site

    Seattle, Washington, 98109, United States

Conditions

The condition(s) this trial relates to.

non-Hodgkin lymphoma plasma cell myeloma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.