Atypical endometrial hyperplasia
Clinical trials for Atypical endometrial hyperplasia explained in plain language.
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Can a Weight-Loss drug boost Fertility-Sparing cancer treatment?
Disease control Not yet recruitingThis trial tests whether adding mazdutide, a weekly injection that helps with weight loss, to a hormonal intrauterine device (IUD) can improve treatment for overweight or obese women with atypical endometrial hyperplasia or early-stage endometrioid endometrial cancer who wish to …
Matched conditions: ATYPICAL ENDOMETRIAL HYPERPLASIA
Phase 2 • Sponsor: Tongji Hospital • Aim: Disease control
Last updated Aug 26, 2026 00:00 UTC
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Could a common Weight-Loss drug help hormone therapy work better for young women with endometrial cancer?
Disease control Not yet recruitingThis trial tests whether adding orlistat, a weight-loss drug that blocks fat absorption, to standard progestin therapy can improve treatment response in young women (45 or younger) with early-stage endometrial cancer or atypical endometrial hyperplasia who have low progesterone r…
Matched conditions: ATYPICAL ENDOMETRIAL HYPERPLASIA
Phase 2 • Sponsor: Peking University People's Hospital • Aim: Disease control
Last updated Jul 22, 2026 00:00 UTC
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Can weight-loss drugs and hormones make endometrial cancer surgery safer for obese women?
Disease control Not yet recruitingThis study tests whether a 28- to 54-week program of weight-loss medication (semaglutide), a hormone-releasing IUD, diet, and exercise is safe and feasible before surgery in women with early endometrial cancer and a BMI of 40 or higher. Eighty participants will be randomly assign…
Matched conditions: ATYPICAL ENDOMETRIAL HYPERPLASIA
Phase 4 • Sponsor: Hospital Universitari de Bellvitge • Aim: Disease control
Last updated Jun 27, 2026 13:07 UTC