ATM gene mutation
Clinical trials for ATM gene mutation explained in plain language.
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Can a Chemo-Targeted drug combo outsmart Treatment-Resistant prostate cancer?
Disease control Stopped earlyThis phase 2 trial is testing whether giving two chemotherapy drugs (docetaxel and carboplatin) followed by a maintenance drug called rucaparib can help men with metastatic castration-resistant prostate cancer that has specific DNA repair defects. The idea is that the chemo shrin…
Matched conditions: ATM GENE MUTATION
Phase 2 • Sponsor: University of Washington • Aim: Disease control
Last updated Aug 28, 2026 00:00 UTC
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Cancer drug niraparib tested before prostate surgery – early trial stopped
Disease control Stopped earlyThis phase II trial tested the drug niraparib (Zejula) in 11 men with high-risk prostate cancer that had not spread. All men had specific DNA repair gene mutations. They took niraparib before having their prostate removed surgically. The goal was to see if the drug could eliminat…
Matched conditions: ATM GENE MUTATION
Phase 2 • Sponsor: University of California, Davis • Aim: Disease control
Last updated Jun 27, 2026 12:33 UTC