ARDS (ACUTE RESPIRATORY DISTRESS SYNDROME)
Clinical trials for ARDS (ACUTE RESPIRATORY DISTRESS SYNDROME) explained in plain language.
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Smart imaging could boost survival in lung failure patients
Disease control Not yet recruitingThis study tests a new way to set breathing machines for adults with severe lung injury (ARDS). Doctors will use a special imaging tool called EIT to tailor ventilator settings to each patient. The goal is to see if this personalized approach lowers the chance of death within 28 …
Matched conditions: ARDS (ACUTE RESPIRATORY DISTRESS SYNDROME)
Phase: NA • Sponsor: Peking Union Medical College Hospital • Aim: Disease control
Last updated May 26, 2026 06:07 UTC
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New inhaled therapy for severe lung failure enters first human tests
Disease control Not yet recruitingThis early-stage study tests a single inhaled dose of a lab-made protein (rhKGF-2) in 24 adults with moderate-to-severe ARDS who are on a breathing machine. The main goal is to see if the drug is safe and tolerable, while also checking for signs it might improve oxygen levels. Pa…
Matched conditions: ARDS (ACUTE RESPIRATORY DISTRESS SYNDROME)
Phase: EARLY_PHASE1 • Sponsor: Shanghai Zhongshan Hospital • Aim: Disease control
Last updated May 26, 2026 06:00 UTC
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Smart ventilation: computer coach aims to save lungs in ICU
Disease control Not yet recruitingThis study tests a computer program that gives real-time feedback to doctors and nurses to help them set ventilators in a way that protects the lungs of critically ill patients. The goal is to see if this approach helps more patients receive lung-protective ventilation, which can…
Matched conditions: ARDS (ACUTE RESPIRATORY DISTRESS SYNDROME)
Phase: NA • Sponsor: Peking Union Medical College Hospital • Aim: Disease control
Last updated May 22, 2026 13:53 UTC
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Muscle relaxant showdown: bolus vs. continuous infusion in ARDS
Disease control Not yet recruitingThis study looks at two methods of giving muscle relaxants to patients with severe lung failure (ARDS) in the ICU. One method gives the drug as needed in small doses, while the other gives it continuously through an IV. The goal is to find out which approach is safer and works be…
Matched conditions: ARDS (ACUTE RESPIRATORY DISTRESS SYNDROME)
Phase: PHASE2 • Sponsor: University of Calgary • Aim: Disease control
Last updated May 22, 2026 13:52 UTC
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Could a common nausea drug prevent lung damage in ventilator patients?
Disease control Not yet recruitingThis study tests whether ondansetron, a drug typically used for nausea, can reduce the strong urge to breathe in patients with acute respiratory distress syndrome (ARDS) on ventilators. This strong drive can cause patients to overwork their lungs, leading to further injury. The t…
Matched conditions: ARDS (ACUTE RESPIRATORY DISTRESS SYNDROME)
Phase: PHASE2, PHASE3 • Sponsor: Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal • Aim: Disease control
Last updated May 18, 2026 12:11 UTC
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New study aims to personalize ventilator settings for lung injury patients
Knowledge-focused Not yet recruitingThis study looks at two different methods for setting the pressure on a breathing machine for people with severe lung injury (ARDS). The goal is to see which method improves oxygen levels better after 24 hours. About 52 adults with moderate to severe ARDS will take part. The find…
Matched conditions: ARDS (ACUTE RESPIRATORY DISTRESS SYNDROME)
Phase: NA • Sponsor: Hospital Dr. Franco Ravera Zunino • Aim: Knowledge-focused
Last updated May 26, 2026 06:07 UTC
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New study aims to unmask hidden lung injury patterns in sepsis patients
Knowledge-focused Not yet recruitingThis study looks at 180 adults with sepsis-related acute respiratory distress syndrome (ARDS), a severe lung condition. Researchers will collect fluid from the lungs and blood samples over three days to measure inflammation and injury markers. The goal is to identify different pa…
Matched conditions: ARDS (ACUTE RESPIRATORY DISTRESS SYNDROME)
Sponsor: Hospital Universitari Vall d'Hebron Research Institute • Aim: Knowledge-focused
Last updated May 22, 2026 14:02 UTC
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New drug HT31-1 takes first step: safety check in healthy volunteers
Knowledge-focused Not yet recruitingThis early-stage study tests the safety of a new drug called HT31-1 in 24 healthy adults aged 18-65. The drug is being developed to treat acute respiratory distress syndrome (ARDS), a severe lung condition. Participants receive a single dose and are monitored for side effects. Th…
Matched conditions: ARDS (ACUTE RESPIRATORY DISTRESS SYNDROME)
Phase: PHASE1 • Sponsor: HTIC, Inc • Aim: Knowledge-focused
Last updated May 22, 2026 13:52 UTC
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Caribbean ECMO registry launches to track Life-Saving machine outcomes
Knowledge-focused Not yet recruitingThis study will collect information from 1,200 patients in the French West Indies and Guiana who have received ECMO, a machine that helps the heart and lungs work. The goal is to understand how these patients fare, including survival rates and complications. No new treatments or …
Matched conditions: ARDS (ACUTE RESPIRATORY DISTRESS SYNDROME)
Sponsor: University of Genova • Aim: Knowledge-focused
Last updated May 22, 2026 13:51 UTC
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New imaging tech aims to spot hidden lung danger in ventilated patients
Knowledge-focused Not yet recruitingThis study will use a new 3D imaging technique (EIT) to observe how blood flow in the lungs switches on and off in a cycle during mechanical ventilation. The goal is to see if this pattern can be detected in 40 adults with moderate to severe ARDS. No treatment is given; the study…
Matched conditions: ARDS (ACUTE RESPIRATORY DISTRESS SYNDROME)
Sponsor: Southeast University, China • Aim: Knowledge-focused
Last updated May 20, 2026 11:53 UTC
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Ventilator settings under the microscope: can we breathe easier?
Knowledge-focused Not yet recruitingThis study looks at how different levels of pressure from a breathing machine (ventilator) affect the lungs and diaphragm in 25 ICU patients with respiratory failure. Each patient will try three pressure settings to see which one helps them breathe more efficiently and with less …
Matched conditions: ARDS (ACUTE RESPIRATORY DISTRESS SYNDROME)
Phase: NA • Sponsor: Vastra Gotaland Region • Aim: Knowledge-focused
Last updated May 18, 2026 12:13 UTC